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C5-Iminosugar modification of casein kinase 1δ lead 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole promotes enhanced inhibitor affinity and selectivity.
Arch Pharm (Weinheim). 2022 May;355(5):e2100497. doi: 10.1002/ardp.202100497. Epub 2022 Feb 17.
Arch Pharm (Weinheim). 2022.
PMID: 35174898
Assessing the Inhibitory Potential of Kinase Inhibitors In Vitro: Major Pitfalls and Suggestions for Improving Comparability of Data Using CK1 Inhibitors as an Example.
Roth A, Gihring A, Göser F, Peifer C, Knippschild U, Bischof J.
Roth A, et al.
Molecules. 2021 Aug 12;26(16):4898. doi: 10.3390/molecules26164898.
Molecules. 2021.
PMID: 34443486
Free PMC article.
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