PG11/109/29247/BHF_/British Heart Foundation/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2012	3
2013	4
2014	1
2015	4
2016	3
2025	0

1

Burke JE, Williams RL. Burke JE, et al. Trends Biochem Sci. 2015 Feb;40(2):88-100. doi: 10.1016/j.tibs.2014.12.003. Epub 2015 Jan 5. Trends Biochem Sci. 2015. PMID: 25573003 Review.

2

PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control.

Walser R, Burke JE, Gogvadze E, Bohnacker T, Zhang X, Hess D, Küenzi P, Leitges M, Hirsch E, Williams RL, Laffargue M, Wymann MP. Walser R, et al. PLoS Biol. 2013;11(6):e1001587. doi: 10.1371/journal.pbio.1001587. Epub 2013 Jun 25. PLoS Biol. 2013. PMID: 23824069 Free PMC article.

3

Connecting with an old partner in a new way.

Burke JE, Williams RL. Burke JE, et al. Cancer Cell. 2013 May 13;23(5):559-61. doi: 10.1016/j.ccr.2013.04.023. Cancer Cell. 2013. PMID: 23680139 Free article.

4

Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.

Rostislavleva K, Soler N, Ohashi Y, Zhang L, Pardon E, Burke JE, Masson GR, Johnson C, Steyaert J, Ktistakis NT, Williams RL. Rostislavleva K, et al. Science. 2015 Oct 9;350(6257):aac7365. doi: 10.1126/science.aac7365. Science. 2015. PMID: 26450213 Free PMC article.

5

Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS).

Burke JE, Williams RL. Burke JE, et al. Adv Biol Regul. 2013 Jan;53(1):97-110. doi: 10.1016/j.jbior.2012.09.005. Epub 2012 Sep 13. Adv Biol Regul. 2013. PMID: 23194976 Free PMC article.

6

Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11.

Fowler ML, McPhail JA, Jenkins ML, Masson GR, Rutaganira FU, Shokat KM, Williams RL, Burke JE. Fowler ML, et al. Protein Sci. 2016 Apr;25(4):826-39. doi: 10.1002/pro.2879. Epub 2016 Feb 1. Protein Sci. 2016. PMID: 26756197 Free PMC article.

7

Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors.

Burke JE, Inglis AJ, Perisic O, Masson GR, McLaughlin SH, Rutaganira F, Shokat KM, Williams RL. Burke JE, et al. Science. 2014 May 30;344(6187):1035-8. doi: 10.1126/science.1253397. Science. 2014. PMID: 24876499 Free PMC article.

8

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).

Vadas O, Dbouk HA, Shymanets A, Perisic O, Burke JE, Abi Saab WF, Khalil BD, Harteneck C, Bresnick AR, Nürnberg B, Backer JM, Williams RL. Vadas O, et al. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18862-7. doi: 10.1073/pnas.1304801110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24190998 Free PMC article.

9

The intrinsically disordered tails of PTEN and PTEN-L have distinct roles in regulating substrate specificity and membrane activity.

Masson GR, Perisic O, Burke JE, Williams RL. Masson GR, et al. Biochem J. 2016 Jan 15;473(2):135-44. doi: 10.1042/BJ20150931. Epub 2015 Nov 2. Biochem J. 2016. PMID: 26527737 Free PMC article.

10

Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA).

Burke JE, Perisic O, Masson GR, Vadas O, Williams RL. Burke JE, et al. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15259-64. doi: 10.1073/pnas.1205508109. Epub 2012 Sep 4. Proc Natl Acad Sci U S A. 2012. PMID: 22949682 Free PMC article.

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