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Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates.
Hermet P, Delache B, Herate C, Wolf E, Kivi G, Juronen E, Mumm K, Žusinaite E, Kainov D, Sankovski E, Virumäe K, Planken A, Merits A, Besaw JE, Yee AW, Morizumi T, Kim K, Kuo A, Berriche A, Dereuddre-Bosquet N, Sconosciuti Q, Naninck T, Relouzat F, Cavarelli M, Ustav M, Wilson D, Ernst OP, Männik A, LeGrand R, Ustav M Jr. Hermet P, et al. PLoS Pathog. 2023 Aug 2;19(8):e1011532. doi: 10.1371/journal.ppat.1011532. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37531329 Free PMC article.
Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD. Sander CL, et al. Structure. 2022 Feb 3;30(2):263-277.e5. doi: 10.1016/j.str.2021.10.002. Epub 2021 Oct 21. Structure. 2022. PMID: 34678158 Free PMC article.