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Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity.
Bharadwaj R, Lusi CF, Mashayekh S, Nagar A, Subbarao M, Kane GI, Wodzanowski KA, Brown AR, Okuda K, Monahan A, Paik D, Nandy A, Anonick MV, Goldman WE, Kanneganti TD, Orzalli MH, Grimes CL, Atukorale PU, Silverman N. Bharadwaj R, et al. Immunity. 2023 May 9;56(5):998-1012.e8. doi: 10.1016/j.immuni.2023.04.001. Epub 2023 Apr 27. Immunity. 2023. PMID: 37116499 Free PMC article.