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Page 1
Free Gangliosides Can Alter Amyloid-β Aggregation.
Chakravorty A, McCalpin SD, Sahoo BR, Ramamoorthy A, Brooks CL 3rd. Chakravorty A, et al. J Phys Chem Lett. 2022 Oct 13;13(40):9303-9308. doi: 10.1021/acs.jpclett.2c02362. Epub 2022 Sep 29. J Phys Chem Lett. 2022. PMID: 36174129 Free PMC article.
hIAPP forms toxic oligomers in plasma.
Rodriguez Camargo DC , Garg D , Buday K , Franko A , Rodriguez Camargo A , Schmidt F , Cox SJ , Suladze S , Haslbeck M , Mideksa YG , Gemmecker G , Aichler M , Mettenleiter G , Schulz M , Walch AK , Hrabě de Angelis M , Feige MJ , Sierra CA , Conrad M , Tripsianes K , Ramamoorthy A , Reif B . Rodriguez Camargo DC , et al. Chem Commun (Camb). 2018 May 24;54(43):5426-5429. doi: 10.1039/c8cc03097a. Chem Commun (Camb). 2018. PMID: 29745410 Free PMC article.
Alzheimer's amyloid-beta intermediates generated using polymer-nanodiscs.
Sahoo BR , Genjo T , Bekier M , Cox SJ , Stoddard AK , Ivanova M , Yasuhara K , Fierke CA , Wang Y , Ramamoorthy A . Sahoo BR , et al. Chem Commun (Camb). 2018 Nov 13;54(91):12883-12886. doi: 10.1039/c8cc07921h. Chem Commun (Camb). 2018. PMID: 30379172 Free PMC article.
Diverse Structural Conversion and Aggregation Pathways of Alzheimer's Amyloid-β (1-40).
Lin Y, Sahoo BR, Ozawa D, Kinoshita M, Kang J, Lim MH, Okumura M, Huh YH, Moon E, Jang JH, Lee HJ, Ryu KY, Ham S, Won HS, Ryu KS, Sugiki T, Bang JK, Hoe HS, Fujiwara T, Ramamoorthy A, Lee YH. Lin Y, et al. ACS Nano. 2019 Aug 27;13(8):8766-8783. doi: 10.1021/acsnano.9b01578. Epub 2019 Jul 24. ACS Nano. 2019. PMID: 31310506 Free PMC article.
Small molecule induced toxic human-IAPP species characterized by NMR.
Cox SJ , Rodriguez Camargo DC , Lee YH , Dubini RCA , Rovó P , Ivanova MI , Padmini V , Reif B , Ramamoorthy A . Cox SJ , et al. Chem Commun (Camb). 2020 Nov 7;56(86):13129-13132. doi: 10.1039/d0cc04803h. Epub 2020 Oct 2. Chem Commun (Camb). 2020. PMID: 33006345 Free PMC article.
43 results