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Page 1
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, Reiman EM, Haroutunian V, Wang M, Schadt E, Zhang B, Dickson DW, Ertekin-Taner N, Golde TE, Petyuk VA, De Jager PL, Bennett DA, Wingo TS, Rangaraju S, Hajjar I, Shulman JM, Lah JJ, Levey AI, Seyfried NT. Johnson ECB, et al. Nat Med. 2020 May;26(5):769-780. doi: 10.1038/s41591-020-0815-6. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284590 Free PMC article.
Sex differences in brain protein expression and disease.
Wingo AP, Liu Y, Gerasimov ES, Vattathil SM, Liu J, Cutler DJ, Epstein MP, Blokland GAM, Thambisetty M, Troncoso JC, Duong DM, Bennett DA, Levey AI, Seyfried NT, Wingo TS. Wingo AP, et al. Nat Med. 2023 Sep;29(9):2224-2232. doi: 10.1038/s41591-023-02509-y. Epub 2023 Aug 31. Nat Med. 2023. PMID: 37653343 Free PMC article.
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease.
Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, Wingo AP, Wingo TS, Chhatwal JP, Day GS, Noble JM, Berman SB, Martins R, Graff-Radford NR, Schofield PR, Ikeuchi T, Mori H, Levin J, Farlow M, Lah JJ, Haass C, Jucker M, Morris JC, Benzinger TLS, Roberts BR, Bateman RJ, Fagan AM, Seyfried NT, Levey AI; Dominantly Inherited Alzheimer Network. Johnson ECB, et al. Nat Med. 2023 Aug;29(8):1979-1988. doi: 10.1038/s41591-023-02476-4. Epub 2023 Aug 7. Nat Med. 2023. PMID: 37550416 Free PMC article.
Role of TET1-mediated epigenetic modulation in Alzheimer's disease.
Armstrong MJ, Jin Y, Vattathil SM, Huang Y, Schroeder JP, Bennet DA, Qin ZS, Wingo TS, Jin P. Armstrong MJ, et al. Neurobiol Dis. 2023 Sep;185:106257. doi: 10.1016/j.nbd.2023.106257. Epub 2023 Aug 8. Neurobiol Dis. 2023. PMID: 37562656 Free PMC article.
Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE ε4 Genotype and Atomoxetine Treatment.
Dammer EB, Shantaraman A, Ping L, Duong DM, Gerasimov ES, Ravindran SP, Gudmundsdottir V, Frick EA, Gomez GT, Walker KA, Emilsson V, Jennings LL, Gudnason V, Western D, Cruchaga C, Lah JJ, Wingo TS, Wingo AP, Seyfried NT, Levey AI, Johnson ECB. Dammer EB, et al. medRxiv [Preprint]. 2023 Oct 30:2023.10.29.23297651. doi: 10.1101/2023.10.29.23297651. medRxiv. 2023. Update in: Sci Transl Med. 2024 Jun 26;16(753):eadn3504. doi: 10.1126/scitranslmed.adn3504. PMID: 37961720 Free PMC article. Updated. Preprint.
Lowering hippocampal miR-29a expression slows cognitive decline and reduces beta-amyloid deposition in 5xFAD mice.
Mei Z, Liu J, Schroeder JP, Weinshenker D, Duong DM, Seyfried NT, Li Y, Jin P, Wingo AP, Wingo TS. Mei Z, et al. Res Sq [Preprint]. 2023 Aug 16:rs.3.rs-3235257. doi: 10.21203/rs.3.rs-3235257/v1. Res Sq. 2023. Update in: Mol Neurobiol. 2024 Jun;61(6):3343-3356. doi: 10.1007/s12035-023-03791-0. PMID: 37645711 Free PMC article. Updated. Preprint.
18 results