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Fixing the Unfixable: The Art of Optimizing Natural Products for Human Medicine.
J Med Chem. 2019 Sep 26;62(18):8412-8428. doi: 10.1021/acs.jmedchem.9b00246. Epub 2019 Apr 26.
J Med Chem. 2019.
PMID: 31026161
Free PMC article.
Review.
Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome.
Limbrick EM, Graf M, Derewacz DK, Nguyen F, Spraggins JM, Wieland M, Ynigez-Gutierrez AE, Reisman BJ, Zinshteyn B, McCulloch KM, Iverson TM, Green R, Wilson DN, Bachmann BO.
Limbrick EM, et al.
J Am Chem Soc. 2020 Oct 28;142(43):18369-18377. doi: 10.1021/jacs.0c04675. Epub 2020 Oct 19.
J Am Chem Soc. 2020.
PMID: 32709196
Free PMC article.
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EvdS6 is a bifunctional decarboxylase from the everninomicin gene cluster.
Dulin CC, Sharma P, Frigo L, Voehler MW, Iverson TM, Bachmann BO.
Dulin CC, et al.
J Biol Chem. 2023 Jul;299(7):104893. doi: 10.1016/j.jbc.2023.104893. Epub 2023 Jun 5.
J Biol Chem. 2023.
PMID: 37286037
Free PMC article.
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