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Page 1
Dendritic cells in cancer immunology.
Murphy TL, Murphy KM. Murphy TL, et al. Cell Mol Immunol. 2022 Jan;19(1):3-13. doi: 10.1038/s41423-021-00741-5. Epub 2021 Sep 3. Cell Mol Immunol. 2022. PMID: 34480145 Free PMC article. Review.
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity.
Ferris ST, Durai V, Wu R, Theisen DJ, Ward JP, Bern MD, Davidson JT 4th, Bagadia P, Liu T, Briseño CG, Li L, Gillanders WE, Wu GF, Yokoyama WM, Murphy TL, Schreiber RD, Murphy KM. Ferris ST, et al. Nature. 2020 Aug;584(7822):624-629. doi: 10.1038/s41586-020-2611-3. Epub 2020 Aug 12. Nature. 2020. PMID: 32788723 Free PMC article.
Mechanisms of CD40-dependent cDC1 licensing beyond costimulation.
Wu R, Ohara RA, Jo S, Liu TT, Ferris ST, Ou F, Kim S, Theisen DJ, Anderson DA 3rd, Wong BW, Gershon T, Schreiber RD, Murphy TL, Murphy KM. Wu R, et al. Nat Immunol. 2022 Nov;23(11):1536-1550. doi: 10.1038/s41590-022-01324-w. Epub 2022 Oct 21. Nat Immunol. 2022. PMID: 36271147 Free PMC article.
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication.
Gargaro M, Scalisi G, Manni G, Briseño CG, Bagadia P, Durai V, Theisen DJ, Kim S, Castelli M, Xu CA, Meyer Zu Hörste G, Servillo G, Della Fazia MA, Mencarelli G, Ricciuti D, Padiglioni E, Giacchè N, Colliva C, Pellicciari R, Calvitti M, Zelante T, Fuchs D, Orabona C, Boon L, Bessede A, Colonna M, Puccetti P, Murphy TL, Murphy KM, Fallarino F. Gargaro M, et al. Immunity. 2022 Jun 14;55(6):1032-1050.e14. doi: 10.1016/j.immuni.2022.05.013. Immunity. 2022. PMID: 35704993 Free PMC article.
Ablation of cDC2 development by triple mutations within the Zeb2 enhancer.
Liu TT, Kim S, Desai P, Kim DH, Huang X, Ferris ST, Wu R, Ou F, Egawa T, Van Dyken SJ, Diamond MS, Johnson PF, Kubo M, Murphy TL, Murphy KM. Liu TT, et al. Nature. 2022 Jul;607(7917):142-148. doi: 10.1038/s41586-022-04866-z. Epub 2022 Jun 22. Nature. 2022. PMID: 35732734 Free PMC article.
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy.
Sultan H, Takeuchi Y, Ward JP, Sharma N, Liu TT, Sukhov V, Firulyova M, Song Y, Ameh S, Brioschi S, Khantakova D, Arthur CD, White JM, Kohlmiller H, Salazar AM, Burns R, Costa HA, Moynihan KD, Yeung YA, Djuretic I, Schumacher TN, Sheehan KCF, Colonna M, Allison JP, Murphy KM, Artyomov MN, Schreiber RD. Sultan H, et al. Nature. 2024 Aug;632(8023):182-191. doi: 10.1038/s41586-024-07752-y. Epub 2024 Jul 24. Nature. 2024. PMID: 39048822 Free PMC article.
The evolving biology of cross-presentation.
Ohara RA, Murphy KM. Ohara RA, et al. Semin Immunol. 2023 Mar;66:101711. doi: 10.1016/j.smim.2023.101711. Epub 2023 Jan 14. Semin Immunol. 2023. PMID: 36645993 Free PMC article. Review.
IL-6 selectively suppresses cDC1 specification via C/EBPβ.
Kim S, Chen J, Jo S, Ou F, Ferris ST, Liu TT, Ohara RA, Anderson DA, Wu R, Chen MY, Gillanders WE, Gillanders WE, Murphy TL, Murphy KM. Kim S, et al. J Exp Med. 2023 Oct 2;220(10):e20221757. doi: 10.1084/jem.20221757. Epub 2023 Jul 11. J Exp Med. 2023. PMID: 37432392 Free PMC article.
30 results