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Sophisticated natural products as antibiotics.
Lewis K, Lee RE, Brötz-Oesterhelt H, Hiller S, Rodnina MV, Schneider T, Weingarth M, Wohlgemuth I. Lewis K, et al. Nature. 2024 Aug;632(8023):39-49. doi: 10.1038/s41586-024-07530-w. Epub 2024 Jul 31. Nature. 2024. PMID: 39085542 Review.
Computational identification of a systemic antibiotic for gram-negative bacteria.
Miller RD, Iinishi A, Modaresi SM, Yoo BK, Curtis TD, Lariviere PJ, Liang L, Son S, Nicolau S, Bargabos R, Morrissette M, Gates MF, Pitt N, Jakob RP, Rath P, Maier T, Malyutin AG, Kaiser JT, Niles S, Karavas B, Ghiglieri M, Bowman SEJ, Rees DC, Hiller S, Lewis K. Miller RD, et al. Nat Microbiol. 2022 Oct;7(10):1661-1672. doi: 10.1038/s41564-022-01227-4. Epub 2022 Sep 26. Nat Microbiol. 2022. PMID: 36163500 Free PMC article.
Mutasynthetic Production and Antimicrobial Characterization of Darobactin Analogs.
Böhringer N, Green R, Liu Y, Mettal U, Marner M, Modaresi SM, Jakob RP, Wuisan ZG, Maier T, Iinishi A, Hiller S, Lewis K, Schäberle TF. Böhringer N, et al. Microbiol Spectr. 2021 Dec 22;9(3):e0153521. doi: 10.1128/spectrum.01535-21. Epub 2021 Dec 22. Microbiol Spectr. 2021. PMID: 34937193 Free PMC article.