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Page 1
Bacteria induce skin regeneration via IL-1β signaling.
Wang G, Sweren E, Liu H, Wier E, Alphonse MP, Chen R, Islam N, Li A, Xue Y, Chen J, Park S, Chen Y, Lee S, Wang Y, Wang S, Archer NK, Andrews W, Kane MA, Dare E, Reddy SK, Hu Z, Grice EA, Miller LS, Garza LA. Wang G, et al. Cell Host Microbe. 2021 May 12;29(5):777-791.e6. doi: 10.1016/j.chom.2021.03.003. Epub 2021 Apr 1. Cell Host Microbe. 2021. PMID: 33798492 Free PMC article.
Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism.
Wang G, Sweren E, Andrews W, Li Y, Chen J, Xue Y, Wier E, Alphonse MP, Luo L, Miao Y, Chen R, Zeng D, Lee S, Li A, Dare E, Kim D, Archer NK, Reddy SK, Resar L, Hu Z, Grice EA, Kane MA, Garza LA. Wang G, et al. Sci Adv. 2023 Jan 4;9(1):eabo7555. doi: 10.1126/sciadv.abo7555. Epub 2023 Jan 4. Sci Adv. 2023. PMID: 36598999 Free PMC article.
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.
Herster F, Bittner Z, Archer NK, Dickhöfer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Löffler MW, Kalbacher H, Vierbuchen T, Heine H, Miller LS, Hartl D, Freund L, Schäkel K, Heister M, Ghoreschi K, Weber ANR. Herster F, et al. Nat Commun. 2020 Jan 8;11(1):105. doi: 10.1038/s41467-019-13756-4. Nat Commun. 2020. PMID: 31913271 Free PMC article.
Staphylococcus aureus proteases trigger eosinophil-mediated skin inflammation.
Kline SN, Orlando NA, Lee AJ, Wu MJ, Zhang J, Youn C, Feller LE, Pontaza C, Dikeman D, Limjunyawong N, Williams KL, Wang Y, Cihakova D, Jacobsen EA, Durum SK, Garza LA, Dong X, Archer NK. Kline SN, et al. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2309243121. doi: 10.1073/pnas.2309243121. Epub 2024 Jan 30. Proc Natl Acad Sci U S A. 2024. PMID: 38289950 Free PMC article.
Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.
Dong X, Limjunyawong N, Sypek EI, Wang G, Ortines RV, Youn C, Alphonse MP, Dikeman D, Wang Y, Lay M, Kothari R, Vasavda C, Pundir P, Goff L, Miller LS, Lu W, Garza LA, Kim BS, Archer NK, Dong X. Dong X, et al. Immunity. 2022 Sep 13;55(9):1645-1662.e7. doi: 10.1016/j.immuni.2022.06.021. Epub 2022 Jul 25. Immunity. 2022. PMID: 35882236 Free PMC article.
Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease.
Patrick GJ, Liu H, Alphonse MP, Dikeman DA, Youn C, Otterson JC, Wang Y, Ravipati A, Mazhar M, Denny G, Ortines RV, Zhang E, Miller RJ, Dillen CA, Liu Q, Nolan SJ, Nguyen K, Marcello L, Do DC, Wier EM, Zhang Y, Caviness G, Klimowicz AC, Mierz DV, Fine JS, Sun G, Goldbach-Mansky R, Marusina AI, Merleev AA, Maverakis E, Garza LA, Milner JD, Gao P, Ramanujam M, Raymond EL, Archer NK, Miller LS. Patrick GJ, et al. J Clin Invest. 2021 Mar 1;131(5):e143334. doi: 10.1172/JCI143334. J Clin Invest. 2021. PMID: 33645549 Free PMC article.
Neutrophil extracellular traps impair regeneration.
Wier E, Asada M, Wang G, Alphonse MP, Li A, Hintelmann C, Sweren E, Youn C, Pielstick B, Ortines R, Lyu C, Daskam M, Miller LS, Archer NK, Garza LA. Wier E, et al. J Cell Mol Med. 2021 Nov;25(21):10008-10019. doi: 10.1111/jcmm.16896. Epub 2021 Oct 8. J Cell Mol Med. 2021. PMID: 34623736 Free PMC article.
naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation.
Bork F, Greve CL, Youn C, Chen S, N C Leal V, Wang Y, Fischer B, Nasri M, Focken J, Scheurer J, Engels P, Dubbelaar M, Hipp K, Zalat B, Szolek A, Wu MJ, Schittek B, Bugl S, Kufer TA, Löffler MW, Chamaillard M, Skokowa J, Kramer D, Archer NK, Weber ANR. Bork F, et al. EMBO Rep. 2024 Jul;25(7):2914-2949. doi: 10.1038/s44319-024-00150-5. Epub 2024 May 23. EMBO Rep. 2024. PMID: 38783164 Free PMC article.
48 results