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Mechanosensitive TRPV4 is required for crystal-induced inflammation.
Lan Z, Chen L, Feng J, Xie Z, Liu Z, Wang F, Liu P, Yue X, Du L, Zhao Y, Yang P, Luo J, Zhu Z, Hu X, Cao L, Lu P, Sah R, Lavine K, Kim B, Hu H. Lan Z, et al. Ann Rheum Dis. 2021 Dec;80(12):1604-1614. doi: 10.1136/annrheumdis-2021-220295. Epub 2021 Oct 18. Ann Rheum Dis. 2021. PMID: 34663597 Free PMC article.
Resident cardiac macrophages mediate adaptive myocardial remodeling.
Wong NR, Mohan J, Kopecky BJ, Guo S, Du L, Leid J, Feng G, Lokshina I, Dmytrenko O, Luehmann H, Bajpai G, Ewald L, Bell L, Patel N, Bredemeyer A, Weinheimer CJ, Nigro JM, Kovacs A, Morimoto S, Bayguinov PO, Fisher MR, Stump WT, Greenberg M, Fitzpatrick JAJ, Epelman S, Kreisel D, Sah R, Liu Y, Hu H, Lavine KJ. Wong NR, et al. Immunity. 2021 Sep 14;54(9):2072-2088.e7. doi: 10.1016/j.immuni.2021.07.003. Epub 2021 Jul 27. Immunity. 2021. PMID: 34320366 Free PMC article.
A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain.
Hu X, Du L, Liu S, Lan Z, Zang K, Feng J, Zhao Y, Yang X, Xie Z, Wang PL, Ver Heul AM, Chen L, Samineni VK, Wang YQ, Lavine KJ, Gereau RW 4th, Wu GF, Hu H. Hu X, et al. J Clin Invest. 2023 Mar 1;133(5):e161507. doi: 10.1172/JCI161507. J Clin Invest. 2023. PMID: 36701202 Free PMC article.
Sensory neurons promote immune homeostasis in the lung.
Tamari M, Del Bel KL, Ver Heul AM, Zamidar L, Orimo K, Hoshi M, Trier AM, Yano H, Yang TL, Biggs CM, Motomura K, Shibuya R, Yu CD, Xie Z, Iriki H, Wang Z, Auyeung K, Damle G, Demircioglu D, Gregory JK, Hasson D, Dai J, Chang RB, Morita H, Matsumoto K, Jain S, Van Dyken S, Milner JD, Bogunovic D, Hu H, Artis D, Turvey SE, Kim BS. Tamari M, et al. Cell. 2024 Jan 4;187(1):44-61.e17. doi: 10.1016/j.cell.2023.11.027. Epub 2023 Dec 21. Cell. 2024. PMID: 38134932 Free article.
IL-33 signaling in sensory neurons promotes dry skin itch.
Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. Trier AM, et al. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. J Allergy Clin Immunol. 2022. PMID: 34560104 Free PMC article.
Ion channel regulation of gut immunity.
Feng J, Xie Z, Hu H. Feng J, et al. J Gen Physiol. 2023 Feb 6;155(2):e202113042. doi: 10.1085/jgp.202113042. Epub 2022 Dec 2. J Gen Physiol. 2023. PMID: 36459135 Free PMC article.
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