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Cancer immunotherapy: the role regulatory T cells play and what can be done to overcome their inhibitory effects.
Curr Mol Med. 2009 Aug;9(6):673-82. doi: 10.2174/156652409788970670.
Curr Mol Med. 2009.
PMID: 19689294
Free PMC article.
Review.
Partial CD4 depletion reduces regulatory T cells induced by multiple vaccinations and restores therapeutic efficacy.
LaCelle MG, Jensen SM, Fox BA.
LaCelle MG, et al.
Clin Cancer Res. 2009 Nov 15;15(22):6881-90. doi: 10.1158/1078-0432.CCR-09-1113. Epub 2009 Nov 10.
Clin Cancer Res. 2009.
PMID: 19903784
Free PMC article.
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Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity.
Petrausch U, Jensen SM, Twitty C, Poehlein CH, Haley DP, Walker EB, Fox BA.
Petrausch U, et al.
J Immunol. 2009 Sep 15;183(6):3682-9. doi: 10.4049/jimmunol.0900560. Epub 2009 Aug 19.
J Immunol. 2009.
PMID: 19692636
Free PMC article.
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Depletion of tumor-induced Treg prior to reconstitution rescues enhanced priming of tumor-specific, therapeutic effector T cells in lymphopenic hosts.
Poehlein CH, Haley DP, Walker EB, Fox BA.
Poehlein CH, et al.
Eur J Immunol. 2009 Nov;39(11):3121-33. doi: 10.1002/eji.200939453.
Eur J Immunol. 2009.
PMID: 19839008
Free PMC article.
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