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The leukemic stem cell.
Jordan CT. Jordan CT. Best Pract Res Clin Haematol. 2007 Mar;20(1):13-8. doi: 10.1016/j.beha.2006.10.005. Best Pract Res Clin Haematol. 2007. PMID: 17336250 Free PMC article. Review.
Preferential induction of apoptosis for primary human leukemic stem cells.
Guzman ML, Swiderski CF, Howard DS, Grimes BA, Rossi RM, Szilvassy SJ, Jordan CT. Guzman ML, et al. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16220-5. doi: 10.1073/pnas.252462599. Epub 2002 Nov 25. Proc Natl Acad Sci U S A. 2002. PMID: 12451177 Free PMC article.
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.
Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT. Guzman ML, et al. Blood. 2007 Dec 15;110(13):4427-35. doi: 10.1182/blood-2007-05-090621. Epub 2007 Sep 5. Blood. 2007. PMID: 17804695 Free PMC article.
Can we finally target the leukemic stem cells?
Jordan CT. Jordan CT. Best Pract Res Clin Haematol. 2008 Dec;21(4):615-20. doi: 10.1016/j.beha.2008.07.006. Best Pract Res Clin Haematol. 2008. PMID: 19041600 Free PMC article.