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A new acycloguanosine-specific supermutant of herpes simplex virus type 1 thymidine kinase suitable for PET imaging and suicide gene therapy for potential use in patients treated with pyrimidine-based cytotoxic drugs.
Likar Y, Dobrenkov K, Olszewska M, Vider E, Shenker L, Cai S, Pillarsetty N, Hricak H, Ponomarev V. Likar Y, et al. J Nucl Med. 2008 May;49(5):713-20. doi: 10.2967/jnumed.107.046425. Epub 2008 Apr 15. J Nucl Med. 2008. PMID: 18413388 Free PMC article.