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Page 1
Fatty acid synthase (FASN) signalome: A molecular guide for precision oncology.
Menendez JA, Cuyàs E, Encinar JA, Vander Steen T, Verdura S, Llop-Hernández À, López J, Serrano-Hervás E, Osuna S, Martin-Castillo B, Lupu R. Menendez JA, et al. Mol Oncol. 2024 Mar;18(3):479-516. doi: 10.1002/1878-0261.13582. Epub 2024 Jan 18. Mol Oncol. 2024. PMID: 38158755 Free PMC article.
Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity.
Cuyàs E, Pedarra S, Verdura S, Pardo MA, Espin Garcia R, Serrano-Hervás E, Llop-Hernández À, Teixidor E, Bosch-Barrera J, López-Bonet E, Martin-Castillo B, Lupu R, Pujana MA, Sardanyès J, Alarcón T, Menendez JA. Cuyàs E, et al. Cell Death Discov. 2024 Sep 30;10(1):417. doi: 10.1038/s41420-024-02184-z. Cell Death Discov. 2024. PMID: 39349429 Free PMC article.
Fatty acid synthase (FASN) regulates the mitochondrial priming of cancer cells.
Schroeder B, Vander Steen T, Espinoza I, Venkatapoorna CMK, Hu Z, Silva FM, Regan K, Cuyàs E, Meng XW, Verdura S, Arbusà A, Schneider PA, Flatten KS, Kemble G, Montero J, Kaufmann SH, Menendez JA, Lupu R. Schroeder B, et al. Cell Death Dis. 2021 Oct 21;12(11):977. doi: 10.1038/s41419-021-04262-x. Cell Death Dis. 2021. PMID: 34675185 Free PMC article.
Fatty Acid Synthase Confers Tamoxifen Resistance to ER+/HER2+ Breast Cancer.
Menendez JA, Papadimitropoulou A, Vander Steen T, Cuyàs E, Oza-Gajera BP, Verdura S, Espinoza I, Vellon L, Mehmi I, Lupu R. Menendez JA, et al. Cancers (Basel). 2021 Mar 6;13(5):1132. doi: 10.3390/cancers13051132. Cancers (Basel). 2021. PMID: 33800852 Free PMC article.
Fatty acid synthase is required for profibrotic TGF-β signaling.
Jung MY, Kang JH, Hernandez DM, Yin X, Andrianifahanana M, Wang Y, Gonzalez-Guerrico A, Limper AH, Lupu R, Leof EB. Jung MY, et al. FASEB J. 2018 Jul;32(7):3803-3815. doi: 10.1096/fj.201701187R. Epub 2018 Feb 16. FASEB J. 2018. PMID: 29475397 Free PMC article.
11 results