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Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens.
Pathangey LB, McCurry DB, Gendler SJ, Dominguez AL, Gorman JE, Pathangey G, Mihalik LA, Dang Y, Disis ML, Cohen PA. Pathangey LB, et al. Oncotarget. 2017 Feb 14;8(7):10785-10808. doi: 10.18632/oncotarget.13911. Oncotarget. 2017. PMID: 27974697 Free PMC article.