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Year Number of Results
2011 4
2012 5
2013 10
2014 9
2015 16
2016 9
2017 13
2018 4
2019 5
2020 7
2021 6
2022 2
2023 1
2024 0

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80 results

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Page 1
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Müschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J. Su R, et al. Cancer Cell. 2020 Jul 13;38(1):79-96.e11. doi: 10.1016/j.ccell.2020.04.017. Epub 2020 Jun 11. Cancer Cell. 2020. PMID: 32531268 Free PMC article.
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.
Qing Y, Dong L, Gao L, Li C, Li Y, Han L, Prince E, Tan B, Deng X, Wetzel C, Shen C, Gao M, Chen Z, Li W, Zhang B, Braas D, Ten Hoeve J, Sanchez GJ, Chen H, Chan LN, Chen CW, Ann D, Jiang L, Müschen M, Marcucci G, Plas DR, Li Z, Su R, Chen J. Qing Y, et al. Mol Cell. 2021 Mar 4;81(5):922-939.e9. doi: 10.1016/j.molcel.2020.12.026. Mol Cell. 2021. PMID: 33434505 Free PMC article.
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally.
Huang H, Weng H, Zhou K, Wu T, Zhao BS, Sun M, Chen Z, Deng X, Xiao G, Auer F, Klemm L, Wu H, Zuo Z, Qin X, Dong Y, Zhou Y, Qin H, Tao S, Du J, Liu J, Lu Z, Yin H, Mesquita A, Yuan CL, Hu YC, Sun W, Su R, Dong L, Shen C, Li C, Qing Y, Jiang X, Wu X, Sun M, Guan JL, Qu L, Wei M, Müschen M, Huang G, He C, Yang J, Chen J. Huang H, et al. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13. Nature. 2019. PMID: 30867593 Free PMC article.
PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma.
Wartewig T, Daniels J, Schulz M, Hameister E, Joshi A, Park J, Morrish E, Venkatasubramani AV, Cernilogar FM, van Heijster FHA, Hundshammer C, Schneider H, Konstantinidis F, Gabler JV, Klement C, Kurniawan H, Law C, Lee Y, Choi S, Guitart J, Forne I, Giustinani J, Müschen M, Jain S, Weinstock DM, Rad R, Ortonne N, Schilling F, Schotta G, Imhof A, Brenner D, Choi J, Ruland J. Wartewig T, et al. Nat Cancer. 2023 Oct;4(10):1508-1525. doi: 10.1038/s43018-023-00635-7. Epub 2023 Sep 18. Nat Cancer. 2023. PMID: 37723306 Free PMC article.
Core transcriptional regulatory circuitries in cancer.
Chen Y, Xu L, Lin RY, Müschen M, Koeffler HP. Chen Y, et al. Oncogene. 2020 Oct;39(43):6633-6646. doi: 10.1038/s41388-020-01459-w. Epub 2020 Sep 17. Oncogene. 2020. PMID: 32943730 Free PMC article. Review.
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.
Pan R, Hogdal LJ, Benito JM, Bucci D, Han L, Borthakur G, Cortes J, DeAngelo DJ, Debose L, Mu H, Döhner H, Gaidzik VI, Galinsky I, Golfman LS, Haferlach T, Harutyunyan KG, Hu J, Leverson JD, Marcucci G, Müschen M, Newman R, Park E, Ruvolo PP, Ruvolo V, Ryan J, Schindela S, Zweidler-McKay P, Stone RM, Kantarjian H, Andreeff M, Konopleva M, Letai AG. Pan R, et al. Cancer Discov. 2014 Mar;4(3):362-75. doi: 10.1158/2159-8290.CD-13-0609. Epub 2013 Dec 17. Cancer Discov. 2014. PMID: 24346116 Free PMC article.
Metabolic determinants of B-cell selection.
Chan LN, Aghania E, Leveille E, Müschen M. Chan LN, et al. Biochem Soc Trans. 2021 Jun 30;49(3):1467-1478. doi: 10.1042/BST20201316. Biochem Soc Trans. 2021. PMID: 34196360 Review.
Signalling input from divergent pathways subverts B cell transformation.
Chan LN, Murakami MA, Robinson ME, Caeser R, Sadras T, Lee J, Cosgun KN, Kume K, Khairnar V, Xiao G, Ahmed MA, Aghania E, Deb G, Hurtz C, Shojaee S, Hong C, Pölönen P, Nix MA, Chen Z, Chen CW, Chen J, Vogt A, Heinäniemi M, Lohi O, Wiita AP, Izraeli S, Geng H, Weinstock DM, Müschen M. Chan LN, et al. Nature. 2020 Jul;583(7818):845-851. doi: 10.1038/s41586-020-2513-4. Epub 2020 Jul 22. Nature. 2020. PMID: 32699415 Free PMC article.
Infectious origins of childhood leukemia.
Swaminathan S, Müschen M. Swaminathan S, et al. Oncotarget. 2015 Jul 10;6(19):16798-9. doi: 10.18632/oncotarget.4630. Oncotarget. 2015. PMID: 26196452 Free PMC article. No abstract available.
80 results