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Year Number of Results
2013 2
2014 6
2015 3
2016 4
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2019 4
2020 2
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2024 4

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28 results

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Page 1
Targeting EZH2 in cancer.
Kim KH, Roberts CW. Kim KH, et al. Nat Med. 2016 Feb;22(2):128-34. doi: 10.1038/nm.4036. Nat Med. 2016. PMID: 26845405 Free PMC article. Review.
Mitotic bookmarking by SWI/SNF subunits.
Zhu Z, Chen X, Guo A, Manzano T, Walsh PJ, Wills KM, Halliburton R, Radko-Juettner S, Carter RD, Partridge JF, Green DR, Zhang J, Roberts CWM. Zhu Z, et al. Nature. 2023 Jun;618(7963):180-187. doi: 10.1038/s41586-023-06085-6. Epub 2023 May 24. Nature. 2023. PMID: 37225980 Free PMC article.
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.
Drosos Y, Myers JA, Xu B, Mathias KM, Beane EC, Radko-Juettner S, Mobley RJ, Larsen ME, Piccioni F, Ma X, Low J, Hansen BS, Peters ST, Bhanu NV, Dhanda SK, Chen T, Upadhyaya SA, Pruett-Miller SM, Root DE, Garcia BA, Partridge JF, Roberts CWM. Drosos Y, et al. Mol Cell. 2022 Jul 7;82(13):2472-2489.e8. doi: 10.1016/j.molcel.2022.04.015. Epub 2022 May 9. Mol Cell. 2022. PMID: 35537449 Free PMC article.
PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression.
Mittal P, Myers JA, Carter RD, Radko-Juettner S, Malone HA, Rosikiewicz W, Robertson AN, Zhu Z, Narayanan IV, Hansen BS, Parrish M, Bhanu NV, Mobley RJ, Rehg JE, Xu B, Drosos Y, Pruett-Miller SM, Ljungman M, Garcia BA, Wu G, Partridge JF, Roberts CWM. Mittal P, et al. Nat Commun. 2024 Aug 24;15(1):7303. doi: 10.1038/s41467-024-51566-5. Nat Commun. 2024. PMID: 39181868 Free PMC article.
Vulnerabilities of mutant SWI/SNF complexes in cancer.
Helming KC, Wang X, Roberts CWM. Helming KC, et al. Cancer Cell. 2014 Sep 8;26(3):309-317. doi: 10.1016/j.ccr.2014.07.018. Cancer Cell. 2014. PMID: 25203320 Free PMC article. Review.
Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.
Radko-Juettner S, Yue H, Myers JA, Carter RD, Robertson AN, Mittal P, Zhu Z, Hansen BS, Donovan KA, Hunkeler M, Rosikiewicz W, Wu Z, McReynolds MG, Roy Burman SS, Schmoker AM, Mageed N, Brown SA, Mobley RJ, Partridge JF, Stewart EA, Pruett-Miller SM, Nabet B, Peng J, Gray NS, Fischer ES, Roberts CWM. Radko-Juettner S, et al. Nature. 2024 Apr;628(8007):442-449. doi: 10.1038/s41586-024-07250-1. Epub 2024 Mar 27. Nature. 2024. PMID: 38538798
28 results