R01 CA177652/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2016	1
2017	1
2018	2
2019	2
2020	1
2021	1
2024	0

1

MT1-MMP-dependent ECM processing regulates laminB1 stability and mediates replication fork restart.

Thakur V, Tiburcio de Freitas J, Li Y, Zhang K, Savadelis A, Bedogni B. Thakur V, et al. PLoS One. 2021 Jul 8;16(7):e0253062. doi: 10.1371/journal.pone.0253062. eCollection 2021. PLoS One. 2021. PMID: 34237080 Free PMC article.

2

Inhibiting Notch1 enhances immunotherapy efficacy in melanoma by preventing Notch1 dependent immune suppressive properties.

Qiu H, Zmina PM, Huang AY, Askew D, Bedogni B. Qiu H, et al. Cancer Lett. 2018 Oct 10;434:144-151. doi: 10.1016/j.canlet.2018.07.024. Epub 2018 Jul 21. Cancer Lett. 2018. PMID: 30036609 Free PMC article.

3

Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma.

Marusak C, Thakur V, Li Y, Freitas JT, Zmina PM, Thakur VS, Chang M, Gao M, Tan J, Xiao M, Lu Y, Mills GB, Flaherty K, Frederick DT, Miao B, Sullivan RJ, Moll T, Boland GM, Herlyn M, Zhang G, Bedogni B. Marusak C, et al. Clin Cancer Res. 2020 Nov 15;26(22):6039-6050. doi: 10.1158/1078-0432.CCR-19-2773. Epub 2020 Aug 20. Clin Cancer Res. 2020. PMID: 32820016 Free PMC article.

4

The membrane tethered matrix metalloproteinase MT1-MMP triggers an outside-in DNA damage response that impacts chemo- and radiotherapy responses of breast cancer.

Thakur V, Zhang K, Savadelis A, Zmina P, Aguila B, Welford SM, Abdul-Karim F, Bonk KW, Keri RA, Bedogni B. Thakur V, et al. Cancer Lett. 2019 Feb 28;443:115-124. doi: 10.1016/j.canlet.2018.11.031. Epub 2018 Nov 29. Cancer Lett. 2019. PMID: 30502358 Free PMC article.

5

Synchronized Targeting of Notch and ERBB Signaling Suppresses Melanoma Tumor Growth through Inhibition of Notch1 and ERBB3.

Zhang K, Wong P, Salvaggio C, Salhi A, Osman I, Bedogni B. Zhang K, et al. J Invest Dermatol. 2016 Feb;136(2):464-472. doi: 10.1016/j.jid.2015.11.006. Epub 2015 Nov 18. J Invest Dermatol. 2016. PMID: 26967479 Free PMC article.

6

ErbB3 Phosphorylation as Central Event in Adaptive Resistance to Targeted Therapy in Metastatic Melanoma: Early Detection in CTCs during Therapy and Insights into Regulation by Autocrine Neuregulin.

Ruggiero CF, Malpicci D, Fattore L, Madonna G, Vanella V, Mallardo D, Liguoro D, Salvati V, Capone M, Bedogni B, Ascierto PA, Mancini R, Ciliberto G. Ruggiero CF, et al. Cancers (Basel). 2019 Sep 25;11(10):1425. doi: 10.3390/cancers11101425. Cancers (Basel). 2019. PMID: 31557826 Free PMC article.

7

The natural compound fucoidan from New Zealand Undaria pinnatifida synergizes with the ERBB inhibitor lapatinib enhancing melanoma growth inhibition.

Thakur V, Lu J, Roscilli G, Aurisicchio L, Cappelletti M, Pavoni E, White WL, Bedogni B. Thakur V, et al. Oncotarget. 2017 Mar 14;8(11):17887-17896. doi: 10.18632/oncotarget.14437. Oncotarget. 2017. PMID: 28060735 Free PMC article.

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