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2015 6
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2019 5
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Page 1
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression.
Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, Kumar S, Garbitt VM, Sharik ME, Henderson KJ, Tonon G, Tomura M, Miwa Y, Esplugues E, Flavell RA, Huber S, Canducci F, Rajkumar VS, Bergsagel PL, Bellone M. Calcinotto A, et al. Nat Commun. 2018 Dec 3;9(1):4832. doi: 10.1038/s41467-018-07305-8. Nat Commun. 2018. PMID: 30510245 Free PMC article.
Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.
Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Ponzoni M, Bossi G, Federico V, La Rosa F, Ricciardi MR, Lesma E, De Meo PD, Castrignanò T, Petrucci MT, Pisani F, Chesi M, Bergsagel PL, Floridi A, Tonon G, Passananti C, Blandino G, Fanciulli M. Desantis A, et al. EMBO J. 2015 May 5;34(9):1214-30. doi: 10.15252/embj.201489920. Epub 2015 Mar 14. EMBO J. 2015. PMID: 25770584 Free PMC article.
IAP antagonists induce anti-tumor immunity in multiple myeloma.
Chesi M, Mirza NN, Garbitt VM, Sharik ME, Dueck AC, Asmann YW, Akhmetzyanova I, Kosiorek HE, Calcinotto A, Riggs DL, Keane N, Ahmann GJ, Morrison KM, Fonseca R, Lacy MQ, Dingli D, Kumar SK, Ailawadhi S, Dispenzieri A, Buadi F, Gertz MA, Reeder CB, Lin Y, Chanan-Khan AA, Stewart AK, Fooksman D, Bergsagel PL. Chesi M, et al. Nat Med. 2016 Dec;22(12):1411-1420. doi: 10.1038/nm.4229. Epub 2016 Nov 14. Nat Med. 2016. PMID: 27841872 Free PMC article. Clinical Trial.
Immunosurveillance and therapy of multiple myeloma are CD226 dependent.
Guillerey C, Ferrari de Andrade L, Vuckovic S, Miles K, Ngiow SF, Yong MC, Teng MW, Colonna M, Ritchie DS, Chesi M, Bergsagel PL, Hill GR, Smyth MJ, Martinet L. Guillerey C, et al. J Clin Invest. 2015 May;125(5):2077-89. doi: 10.1172/JCI77181. Epub 2015 Apr 20. J Clin Invest. 2015. PMID: 25893601 Free PMC article.
Antigen-mediated regulation in monoclonal gammopathies and myeloma.
Nair S, Sng J, Boddupalli CS, Seckinger A, Chesi M, Fulciniti M, Zhang L, Rauniyar N, Lopez M, Neparidze N, Parker T, Munshi NC, Sexton R, Barlogie B, Orlowski R, Bergsagel L, Hose D, Flavell RA, Mistry PK, Meffre E, Dhodapkar MV. Nair S, et al. JCI Insight. 2018 Apr 19;3(8):e98259. doi: 10.1172/jci.insight.98259. eCollection 2018 Apr 19. JCI Insight. 2018. PMID: 29669929 Free PMC article. Clinical Trial.
Bone marrow transplantation generates T cell-dependent control of myeloma in mice.
Vuckovic S, Minnie SA, Smith D, Gartlan KH, Watkins TS, Markey KA, Mukhopadhyay P, Guillerey C, Kuns RD, Locke KR, Pritchard AL, Johansson PA, Varelias A, Zhang P, Huntington ND, Waddell N, Chesi M, Miles JJ, Smyth MJ, Hill GR. Vuckovic S, et al. J Clin Invest. 2019 Jan 2;129(1):106-121. doi: 10.1172/JCI98888. Epub 2018 Nov 19. J Clin Invest. 2019. PMID: 30300141 Free PMC article.
Oncolytic immunotherapy and bortezomib synergy improves survival of refractory multiple myeloma in a preclinical model.
Thirukkumaran CM, Shi ZQ, Nuovo GJ, Luider J, Kopciuk KA, Dong Y, Mostafa AA, Thakur S, Gratton K, Yang A, Chin AC, Coffey MC, Jimenez-Zepeda VH, Stewart D, Chesi M, Bergsagel PL, Morris D. Thirukkumaran CM, et al. Blood Adv. 2019 Mar 12;3(5):797-812. doi: 10.1182/bloodadvances.2018025593. Blood Adv. 2019. PMID: 30850386 Free PMC article.
20 results