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26 results

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Page 1
Increased glucose availability sensitizes pancreatic cancer to chemotherapy.
Vaziri-Gohar A, Hue JJ, Abbas A, Graor HJ, Hajihassani O, Zarei M, Titomihelakis G, Feczko J, Rathore M, Chelstowska S, Loftus AW, Wang R, Zarei M, Goudarzi M, Zhang R, Willard B, Zhang L, Kresak A, Willis JE, Wang GM, Tatsuoka C, Salvino JM, Bederman I, Brunengraber H, Lyssiotis CA, Brody JR, Winter JM. Vaziri-Gohar A, et al. Nat Commun. 2023 Jun 28;14(1):3823. doi: 10.1038/s41467-023-38921-8. Nat Commun. 2023. PMID: 37380658 Free PMC article.
Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer.
Li Y, Wu S, Zhao Y, Dinh T, Jiang D, Selfridge JE, Myers G, Wang Y, Zhao X, Tomchuck S, Dubyak G, Lee RT, Estfan B, Shapiro M, Kamath S, Mohamed A, Huang SC, Huang AY, Conlon R, Krishnamurthi S, Eads J, Willis JE, Khorana AA, Bajor D, Wang Z. Li Y, et al. J Clin Invest. 2024 Jan 9;134(5):e175031. doi: 10.1172/JCI175031. J Clin Invest. 2024. PMID: 38194275 Free PMC article.
Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling.
Rathore M, Curry K, Huang W, Wright M, Martin D, Baek J, Taylor D, Miyagi M, Tang W, Feng H, Li Y, Wang Z, Graor H, Willis J, Bryson E, Boutros CS, Desai O, Islam BN, Ellis LM, Moss SE, Winter JM, Greenwood J, Wang R. Rathore M, et al. Gastroenterology. 2024 Oct 10:S0016-5085(24)05566-5. doi: 10.1053/j.gastro.2024.10.004. Online ahead of print. Gastroenterology. 2024. PMID: 39393543 Free article.
ELF3 is an antagonist of oncogenic-signalling-induced expression of EMT-TF ZEB1.
Liu D, Skomorovska Y, Song J, Bowler E, Harris R, Ravasz M, Bai S, Ayati M, Tamai K, Koyuturk M, Yuan X, Wang Z, Wang Y, Ewing RM. Liu D, et al. Cancer Biol Ther. 2019;20(1):90-100. doi: 10.1080/15384047.2018.1507256. Epub 2018 Aug 27. Cancer Biol Ther. 2019. PMID: 30148686 Free PMC article.
Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.
Vaziri-Gohar A, Cassel J, Mohammed FS, Zarei M, Hue JJ, Hajihassani O, Graor HJ, Srikanth YVV, Karim SA, Abbas A, Prendergast E, Chen V, Katayama ES, Dukleska K, Khokhar I, Andren A, Zhang L, Wu C, Erokwu B, Flask CA, Zarei M, Wang R, Rothermel LD, Romani AMP, Bowers J, Getts R, Tatsuoka C, Morton JP, Bederman I, Brunengraber H, Lyssiotis CA, Salvino JM, Brody JR, Winter JM. Vaziri-Gohar A, et al. Nat Cancer. 2022 Jul;3(7):852-865. doi: 10.1038/s43018-022-00393-y. Epub 2022 Jun 9. Nat Cancer. 2022. PMID: 35681100 Free PMC article.
5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against PIK3CA-Mutant Colorectal Cancers.
Zhao Y, Feng X, Chen Y, Selfridge JE, Gorityala S, Du Z, Wang JM, Hao Y, Cioffi G, Conlon RA, Barnholtz-Sloan JS, Saltzman J, Krishnamurthi SS, Vinayak S, Veigl M, Xu Y, Bajor DL, Markowitz SD, Meropol NJ, Eads JR, Wang Z. Zhao Y, et al. Cancer Res. 2020 Nov 1;80(21):4815-4827. doi: 10.1158/0008-5472.CAN-20-0600. Epub 2020 Sep 9. Cancer Res. 2020. PMID: 32907836 Free PMC article. Clinical Trial.
26 results