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Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
Cannon AC, Budagyan K, Uribe-Alvarez C, Kurimchak AM, Araiza-Olivera D, Cai KQ, Peri S, Zhou Y, Duncan JS, Chernoff J. Cannon AC, et al. bioRxiv [Preprint]. 2023 Jun 28:2023.06.27.546707. doi: 10.1101/2023.06.27.546707. bioRxiv. 2023. Update in: Oncogene. 2024 Mar;43(10):729-743. doi: 10.1038/s41388-024-02947-z. PMID: 37425776 Free PMC article. Updated. Preprint.
Kinome Profiling of Primary Endometrial Tumors Using Multiplexed Inhibitor Beads and Mass Spectrometry Identifies SRPK1 as Candidate Therapeutic Target.
Kurimchak AM, Kumar V, Herrera-Montávez C, Johnson KJ, Srivastava N, Davarajan K, Peri S, Cai KQ, Mantia-Smaldone GM, Duncan JS. Kurimchak AM, et al. Mol Cell Proteomics. 2020 Dec;19(12):2068-2090. doi: 10.1074/mcp.RA120.002012. Epub 2020 Sep 29. Mol Cell Proteomics. 2020. PMID: 32994315 Free PMC article.
Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma.
Kurimchak AM, Herrera-Montávez C, Brown J, Johnson KJ, Sodi V, Srivastava N, Kumar V, Deihimi S, O'Brien S, Peri S, Mantia-Smaldone GM, Jain A, Winters RM, Cai KQ, Chernoff J, Connolly DC, Duncan JS. Kurimchak AM, et al. Sci Signal. 2020 Feb 18;13(619):eaax8238. doi: 10.1126/scisignal.aax8238. Sci Signal. 2020. PMID: 32071169 Free PMC article.
13 results