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17 results

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Page 1
Acetyl-CoA metabolism in cancer.
Guertin DA, Wellen KE. Guertin DA, et al. Nat Rev Cancer. 2023 Mar;23(3):156-172. doi: 10.1038/s41568-022-00543-5. Epub 2023 Jan 19. Nat Rev Cancer. 2023. PMID: 36658431 Free PMC article. Review.
Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.
Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller KD, Schug ZT, Snyder NW, Gade TP, Titchenell PM, Rabinowitz JD, Wellen KE. Zhao S, et al. Nature. 2020 Mar;579(7800):586-591. doi: 10.1038/s41586-020-2101-7. Epub 2020 Mar 18. Nature. 2020. PMID: 32214246 Free PMC article.
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Carrer A, Trefely S, Zhao S, Campbell SL, Norgard RJ, Schultz KC, Sidoli S, Parris JLD, Affronti HC, Sivanand S, Egolf S, Sela Y, Trizzino M, Gardini A, Garcia BA, Snyder NW, Stanger BZ, Wellen KE. Carrer A, et al. Cancer Discov. 2019 Mar;9(3):416-435. doi: 10.1158/2159-8290.CD-18-0567. Epub 2019 Jan 9. Cancer Discov. 2019. PMID: 30626590 Free PMC article.
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis.
Izzo LT, Trefely S, Demetriadou C, Drummond JM, Mizukami T, Kuprasertkul N, Farria AT, Nguyen PTT, Murali N, Reich L, Kantner DS, Shaffer J, Affronti H, Carrer A, Andrews A, Capell BC, Snyder NW, Wellen KE. Izzo LT, et al. Sci Adv. 2023 May 3;9(18):eadf0115. doi: 10.1126/sciadv.adf0115. Epub 2023 May 3. Sci Adv. 2023. PMID: 37134161 Free PMC article.
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation.
Trefely S, Huber K, Liu J, Noji M, Stransky S, Singh J, Doan MT, Lovell CD, von Krusenstiern E, Jiang H, Bostwick A, Pepper HL, Izzo L, Zhao S, Xu JP, Bedi KC Jr, Rame JE, Bogner-Strauss JG, Mesaros C, Sidoli S, Wellen KE, Snyder NW. Trefely S, et al. Mol Cell. 2022 Jan 20;82(2):447-462.e6. doi: 10.1016/j.molcel.2021.11.006. Epub 2021 Dec 1. Mol Cell. 2022. PMID: 34856123 Free PMC article.
Metabolic Signaling to the Nucleus in Cancer.
Campbell SL, Wellen KE. Campbell SL, et al. Mol Cell. 2018 Aug 2;71(3):398-408. doi: 10.1016/j.molcel.2018.07.015. Mol Cell. 2018. PMID: 30075141 Free article. Review.
O-GlcNAc transferase regulates glioblastoma acetate metabolism via regulation of CDK5-dependent ACSS2 phosphorylation.
Ciraku L, Bacigalupa ZA, Ju J, Moeller RA, Le Minh G, Lee RH, Smith MD, Ferrer CM, Trefely S, Izzo LT, Doan MT, Gocal WA, D'Agostino L, Shi W, Jackson JG, Katsetos CD, Wellen KE, Snyder NW, Reginato MJ. Ciraku L, et al. Oncogene. 2022 Apr;41(14):2122-2136. doi: 10.1038/s41388-022-02237-6. Epub 2022 Feb 22. Oncogene. 2022. PMID: 35190642 Free PMC article.
17 results