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2023 5
2024 2

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Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
Morris JA, Caragine C, Daniloski Z, Domingo J, Barry T, Lu L, Davis K, Ziosi M, Glinos DA, Hao S, Mimitou EP, Smibert P, Roeder K, Katsevich E, Lappalainen T, Sanjana NE. Morris JA, et al. Science. 2023 May 19;380(6646):eadh7699. doi: 10.1126/science.adh7699. Epub 2023 May 19. Science. 2023. PMID: 37141313 Free PMC article.
Essential transcription factors for induced neuron differentiation.
Lu C, Garipler G, Dai C, Roush T, Salome-Correa J, Martin A, Liscovitch-Brauer N, Mazzoni EO, Sanjana NE. Lu C, et al. Nat Commun. 2023 Dec 15;14(1):8362. doi: 10.1038/s41467-023-43602-7. Nat Commun. 2023. PMID: 38102126 Free PMC article.
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.
Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H. Ferrarone JR, et al. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2403685121. doi: 10.1073/pnas.2403685121. Epub 2024 May 14. Proc Natl Acad Sci U S A. 2024. PMID: 38743625 Free PMC article.