R01 DA010770/DA/NIDA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2000	2
2004	1
2007	2
2008	1
2009	3
2011	2
2025	0

1

14-O-Heterocyclic-substituted naltrexone derivatives as non-peptide mu opioid receptor selective antagonists: design, synthesis, and biological studies.

Li G, Aschenbach LC, He H, Selley DE, Zhang Y. Li G, et al. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1825-9. doi: 10.1016/j.bmcl.2008.12.093. Epub 2008 Dec 29. Bioorg Med Chem Lett. 2009. PMID: 19217280 Free PMC article.

2

Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists.

Li G, Aschenbach LC, Chen J, Cassidy MP, Stevens DL, Gabra BH, Selley DE, Dewey WL, Westkaemper RB, Zhang Y. Li G, et al. J Med Chem. 2009 Mar 12;52(5):1416-27. doi: 10.1021/jm801272c. J Med Chem. 2009. PMID: 19199782 Free PMC article.

3

Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS.

Sim-Selley LJ, Goforth PB, Mba MU, Macdonald TL, Lynch KR, Milstien S, Spiegel S, Satin LS, Welch SP, Selley DE. Sim-Selley LJ, et al. J Neurochem. 2009 Aug;110(4):1191-202. doi: 10.1111/j.1471-4159.2009.06202.x. Epub 2009 May 31. J Neurochem. 2009. PMID: 19493165 Free PMC article.

4

Chronic heroin self-administration desensitizes mu opioid receptor-activated G-proteins in specific regions of rat brain.

Sim-Selley LJ, Selley DE, Vogt LJ, Childers SR, Martin TJ. Sim-Selley LJ, et al. J Neurosci. 2000 Jun 15;20(12):4555-62. doi: 10.1523/JNEUROSCI.20-12-04555.2000. J Neurosci. 2000. PMID: 10844025 Free PMC article.

5

Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens.

Sim-Selley LJ, Cassidy MP, Sparta A, Zachariou V, Nestler EJ, Selley DE. Sim-Selley LJ, et al. Neuropharmacology. 2011 Dec;61(8):1470-6. doi: 10.1016/j.neuropharm.2011.08.046. Epub 2011 Sep 3. Neuropharmacology. 2011. PMID: 21907220 Free PMC article.

6

Mice with deficiency of G protein gamma3 are lean and have seizures.

Schwindinger WF, Giger KE, Betz KS, Stauffer AM, Sunderlin EM, Sim-Selley LJ, Selley DE, Bronson SK, Robishaw JD. Schwindinger WF, et al. Mol Cell Biol. 2004 Sep;24(17):7758-68. doi: 10.1128/MCB.24.17.7758-7768.2004. Mol Cell Biol. 2004. PMID: 15314181 Free PMC article.

7

Chronic neuropathic pain in mice reduces μ-opioid receptor-mediated G-protein activity in the thalamus.

Hoot MR, Sim-Selley LJ, Selley DE, Scoggins KL, Dewey WL. Hoot MR, et al. Brain Res. 2011 Aug 11;1406:1-7. doi: 10.1016/j.brainres.2011.06.023. Epub 2011 Jun 16. Brain Res. 2011. PMID: 21762883 Free PMC article.

8

Effects of sodium on agonist efficacy for G-protein activation in mu-opioid receptor-transfected CHO cells and rat thalamus.

Selley DE, Cao CC, Liu Q, Childers SR. Selley DE, et al. Br J Pharmacol. 2000 Jul;130(5):987-96. doi: 10.1038/sj.bjp.0703382. Br J Pharmacol. 2000. PMID: 10882382 Free PMC article.

9

Low dose combination of morphine and delta9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors.

Smith PA, Selley DE, Sim-Selley LJ, Welch SP. Smith PA, et al. Eur J Pharmacol. 2007 Oct 1;571(2-3):129-37. doi: 10.1016/j.ejphar.2007.06.001. Epub 2007 Jun 12. Eur J Pharmacol. 2007. PMID: 17603035 Free PMC article.

10

Region-dependent attenuation of mu opioid receptor-mediated G-protein activation in mouse CNS as a function of morphine tolerance.

Sim-Selley LJ, Scoggins KL, Cassidy MP, Smith LA, Dewey WL, Smith FL, Selley DE. Sim-Selley LJ, et al. Br J Pharmacol. 2007 Aug;151(8):1324-33. doi: 10.1038/sj.bjp.0707328. Epub 2007 Jun 18. Br J Pharmacol. 2007. PMID: 17572699 Free PMC article.

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