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Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Cell Metab. 2010 May 5;11(5):390-401. doi: 10.1016/j.cmet.2010.03.014.
Cell Metab. 2010.
PMID: 20444419
Free PMC article.
S6K1 plays a critical role in early adipocyte differentiation.
Carnevalli LS, Masuda K, Frigerio F, Le Bacquer O, Um SH, Gandin V, Topisirovic I, Sonenberg N, Thomas G, Kozma SC.
Carnevalli LS, et al.
Dev Cell. 2010 May 18;18(5):763-74. doi: 10.1016/j.devcel.2010.02.018.
Dev Cell. 2010.
PMID: 20493810
Free PMC article.
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