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Emerging immunomodulatory strategies for cell therapeutics.
Chua CYX, Jiang AY, Eufrásio-da-Silva T, Dolatshahi-Pirouz A, Langer R, Orive G, Grattoni A. Chua CYX, et al. Trends Biotechnol. 2023 Mar;41(3):358-373. doi: 10.1016/j.tibtech.2022.11.008. Epub 2022 Dec 20. Trends Biotechnol. 2023. PMID: 36549959 Free article. Review.
Engineering platforms for localized long-acting immune modulation.
Chua CYX, Viswanath DI, Huston DP, Grattoni A. Chua CYX, et al. J Allergy Clin Immunol. 2024 Mar;153(3):572-575. doi: 10.1016/j.jaci.2024.01.004. Epub 2024 Jan 20. J Allergy Clin Immunol. 2024. PMID: 38253261 Free article. Review.
Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead.
Grattoni A, Korbutt G, Tomei AA, García AJ, Pepper AR, Stabler C, Brehm M, Papas K, Citro A, Shirwan H, Millman JR, Melero-Martin J, Graham M, Sefton M, Ma M, Kenyon N, Veiseh O, Desai TA, Nostro MC, Marinac M, Sykes M, Russ HA, Odorico J, Tang Q, Ricordi C, Latres E, Mamrak NE, Giraldo J, Poznansky MC, de Vos P. Grattoni A, et al. Nat Rev Endocrinol. 2025 Jan;21(1):14-30. doi: 10.1038/s41574-024-01029-0. Epub 2024 Sep 3. Nat Rev Endocrinol. 2025. PMID: 39227741 Review.
Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats.
Paez-Mayorga J, Campa-Carranza JN, Capuani S, Hernandez N, Liu HC, Chua CYX, Pons-Faudoa FP, Malgir G, Alvarez B, Niles JA, Argueta LB, Shelton KA, Kezar S, Nehete PN, Berman DM, Willman MA, Li XC, Ricordi C, Nichols JE, Gaber AO, Kenyon NS, Grattoni A. Paez-Mayorga J, et al. Nat Commun. 2022 Dec 26;13(1):7951. doi: 10.1038/s41467-022-35629-z. Nat Commun. 2022. PMID: 36572684 Free PMC article.
Hybridizing mechanistic mathematical modeling with deep learning methods to predict individual cancer patient survival after immune checkpoint inhibitor therapy.
Butner JD, Dogra P, Chung C, Koay EJ, Welsh JW, Hong DS, Cristini V, Wang Z. Butner JD, et al. Res Sq [Preprint]. 2024 Mar 29:rs.3.rs-4151883. doi: 10.21203/rs.3.rs-4151883/v1. Res Sq. 2024. Update in: NPJ Syst Biol Appl. 2024 Aug 14;10(1):88. doi: 10.1038/s41540-024-00415-8 PMID: 38586046 Free PMC article. Updated. Preprint.
12 results