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TGFB1 induces fetal reprogramming and enhances intestinal regeneration.
Chen L, Qiu X, Dupre A, Pellon-Cardenas O, Fan X, Xu X, Rout P, Walton KD, Burclaff J, Zhang R, Fang W, Ofer R, Logerfo A, Vemuri K, Bandyopadhyay S, Wang J, Barbet G, Wang Y, Gao N, Perekatt AO, Hu W, Magness ST, Spence JR, Verzi MP. Chen L, et al. Cell Stem Cell. 2023 Nov 2;30(11):1520-1537.e8. doi: 10.1016/j.stem.2023.09.015. Epub 2023 Oct 20. Cell Stem Cell. 2023. PMID: 37865088 Free PMC article.
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon.
Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han L, Campbell I, Mahe MM, McCauley HA, Zhang X, Sundaram N, Hudson JR, Zarsozo-Lacoste A, Pradhan S, Tominaga K, Sanchez JG, Weiss AA, Chatuvedi P, Spence JR, Hachimi M, North T, Daley GQ, Mayhew CN, Hu YC, Takebe T, Helmrath MA, Wells JM. Múnera JO, et al. Cell Stem Cell. 2023 Nov 2;30(11):1434-1451.e9. doi: 10.1016/j.stem.2023.10.002. Cell Stem Cell. 2023. PMID: 37922878 Free PMC article.
In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice.
Bouffi C, Wikenheiser-Brokamp KA, Chaturvedi P, Sundaram N, Goddard GR, Wunderlich M, Brown NE, Staab JF, Latanich R, Zachos NC, Holloway EM, Mahe MM, Poling HM, Vales S, Fisher GW, Spence JR, Mulloy JC, Zorn AM, Wells JM, Helmrath MA. Bouffi C, et al. Nat Biotechnol. 2023 Jun;41(6):824-831. doi: 10.1038/s41587-022-01558-x. Epub 2023 Jan 26. Nat Biotechnol. 2023. PMID: 36702898 Free PMC article.
EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids.
Childs CJ, Holloway EM, Sweet CW, Tsai YH, Wu A, Vallie A, Eiken MK, Capeling MM, Zwick RK, Palikuqi B, Trentesaux C, Wu JH, Pellón-Cardenas O, Zhang CJ, Glass I, Loebel C, Yu Q, Camp JG, Sexton JZ, Klein OD, Verzi MP, Spence JR. Childs CJ, et al. JCI Insight. 2023 Mar 22;8(6):e165566. doi: 10.1172/jci.insight.165566. JCI Insight. 2023. PMID: 36821371 Free PMC article.