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A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate.
Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, Ferroni L, Zhang Y, Jung Y, Sales G, Martini P, Nakamura T, Lasorsa FM, Finkel T, Lin CP, Zavan B, Pinton P, Georgakoudi I, Romualdi C, Scadden DT, Ito K. Bonora M, et al. Cell Stem Cell. 2024 Mar 7;31(3):359-377.e10. doi: 10.1016/j.stem.2024.02.004. Cell Stem Cell. 2024. PMID: 38458178 Free article.
Label-Free Optical Metabolic Imaging in Cells and Tissues.
Georgakoudi I, Quinn KP. Georgakoudi I, et al. Annu Rev Biomed Eng. 2023 Jun 8;25:413-443. doi: 10.1146/annurev-bioeng-071516-044730. Epub 2023 Apr 27. Annu Rev Biomed Eng. 2023. PMID: 37104650 Free PMC article. Review.
Restoration of metabolic functional metrics from label-free, two-photon cervical tissue images using multiscale deep-learning-based denoising algorithms.
Vora N, Polleys CM, Sakellariou F, Georgalis G, Thieu HT, Genega EM, Jahanseir N, Patra A, Miller E, Georgakoudi I. Vora N, et al. bioRxiv [Preprint]. 2023 Jun 9:2023.06.07.544033. doi: 10.1101/2023.06.07.544033. bioRxiv. 2023. Update in: J Biomed Opt. 2023 Dec;28(12):126006. doi: 10.1117/1.JBO.28.12.126006. PMID: 37333366 Free PMC article. Updated. Preprint.
Formalin fixation and paraffin embedding interfere with preservation of optical metabolic assessments based on endogenous NAD(P)H and FAD two photon excited fluorescence.
Sánchez-Hernández A, Polleys CM, Georgakoudi I. Sánchez-Hernández A, et al. bioRxiv [Preprint]. 2023 Jun 17:2023.06.16.545363. doi: 10.1101/2023.06.16.545363. bioRxiv. 2023. Update in: Biomed Opt Express. 2023 Sep 15;14(10):5238-5253. doi: 10.1364/BOE.498297. PMID: 37398103 Free PMC article. Updated. Preprint.