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Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.
Curr Opin Cell Biol. 2009 Apr;21(2):245-55. doi: 10.1016/j.ceb.2009.01.018. Epub 2009 Feb 21.
Curr Opin Cell Biol. 2009.
PMID: 19230643
Free PMC article.
Review.
p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.
Reinhardt HC, Aslanian AS, Lees JA, Yaffe MB.
Reinhardt HC, et al.
Cancer Cell. 2007 Feb;11(2):175-89. doi: 10.1016/j.ccr.2006.11.024.
Cancer Cell. 2007.
PMID: 17292828
Free PMC article.
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