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Page 1
Mechanisms of age-related macular degeneration.
Ambati J, Fowler BJ. Ambati J, et al. Neuron. 2012 Jul 12;75(1):26-39. doi: 10.1016/j.neuron.2012.06.018. Neuron. 2012. PMID: 22794258 Free PMC article. Review.
Drusen complement components C3a and C5a promote choroidal neovascularization.
Nozaki M, Raisler BJ, Sakurai E, Sarma JV, Barnum SR, Lambris JD, Chen Y, Zhang K, Ambati BK, Baffi JZ, Ambati J. Nozaki M, et al. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2328-33. doi: 10.1073/pnas.0408835103. Epub 2006 Feb 1. Proc Natl Acad Sci U S A. 2006. PMID: 16452172 Free PMC article.
Fifty years later: the disk goes to the prom.
Kleinman ME, Ambati J. Kleinman ME, et al. J Clin Invest. 2008 Aug;118(8):2681-4. doi: 10.1172/JCI36515. J Clin Invest. 2008. PMID: 18654671 Free PMC article.
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baffi JZ, Albuquerque RJ, Yamasaki S, Itaya M, Pan Y, Appukuttan B, Gibbs D, Yang Z, Karikó K, Ambati BK, Wilgus TA, DiPietro LA, Sakurai E, Zhang K, Smith JR, Taylor EW, Ambati J. Kleinman ME, et al. Nature. 2008 Apr 3;452(7187):591-7. doi: 10.1038/nature06765. Epub 2008 Mar 26. Nature. 2008. PMID: 18368052 Free PMC article.
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J. Takeda A, et al. Nature. 2009 Jul 9;460(7252):225-30. doi: 10.1038/nature08151. Epub 2009 Jun 14. Nature. 2009. PMID: 19525930 Free PMC article.
Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.
Albuquerque RJ, Hayashi T, Cho WG, Kleinman ME, Dridi S, Takeda A, Baffi JZ, Yamada K, Kaneko H, Green MG, Chappell J, Wilting J, Weich HA, Yamagami S, Amano S, Mizuki N, Alexander JS, Peterson ML, Brekken RA, Hirashima M, Capoor S, Usui T, Ambati BK, Ambati J. Albuquerque RJ, et al. Nat Med. 2009 Sep;15(9):1023-30. doi: 10.1038/nm.2018. Epub 2009 Aug 9. Nat Med. 2009. PMID: 19668192 Free PMC article.