R01 GM118833/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	4
2017	9
2018	6
2019	4
2020	5
2021	3
2022	3
2023	1
2024	1

1

DNA repair defects in cancer and therapeutic opportunities.

Hopkins JL, Lan L, Zou L. Hopkins JL, et al. Genes Dev. 2022 Mar 1;36(5-6):278-293. doi: 10.1101/gad.349431.122. Genes Dev. 2022. PMID: 35318271 Free PMC article. Review.

2

Sources, resolution and physiological relevance of R-loops and RNA-DNA hybrids.

Petermann E, Lan L, Zou L. Petermann E, et al. Nat Rev Mol Cell Biol. 2022 Aug;23(8):521-540. doi: 10.1038/s41580-022-00474-x. Epub 2022 Apr 22. Nat Rev Mol Cell Biol. 2022. PMID: 35459910 Review.

3

The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.

Yang H, Lachtara EM, Ran X, Hopkins J, Patel PS, Zhu X, Xiao Y, Phoon L, Gao B, Zou L, Lawrence MS, Lan L. Yang H, et al. Nat Commun. 2023 Sep 30;14(1):6114. doi: 10.1038/s41467-023-41790-w. Nat Commun. 2023. PMID: 37777505 Free PMC article.

4

RNA transcripts stimulate homologous recombination by forming DR-loops.

Ouyang J, Yadav T, Zhang JM, Yang H, Rheinbay E, Guo H, Haber DA, Lan L, Zou L. Ouyang J, et al. Nature. 2021 Jun;594(7862):283-288. doi: 10.1038/s41586-021-03538-8. Epub 2021 May 12. Nature. 2021. PMID: 33981036 Free PMC article.

5

FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation.

Yang H, Wang Y, Xiang Y, Yadav T, Ouyang J, Phoon L, Zhu X, Shi Y, Zou L, Lan L. Yang H, et al. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2116251119. doi: 10.1073/pnas.2116251119. Epub 2022 Mar 15. Proc Natl Acad Sci U S A. 2022. PMID: 35290126 Free PMC article.

6

Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.

Wang Y, Gao B, Zhang L, Wang X, Zhu X, Yang H, Zhang F, Zhu X, Zhou B, Yao S, Nagayama A, Lee S, Ouyang J, Koh SB, Eisenhauer EL, Zarrella D, Lu K, Rueda BR, Zou L, Su XA, Yeku O, Ellisen LW, Wang XS, Lan L. Wang Y, et al. Nat Commun. 2024 Feb 21;15(1):1568. doi: 10.1038/s41467-024-45693-2. Nat Commun. 2024. PMID: 38383600 Free PMC article.

7

Transcription-coupled homologous recombination after oxidative damage.

Wei L, Levine AS, Lan L. Wei L, et al. DNA Repair (Amst). 2016 Aug;44:76-80. doi: 10.1016/j.dnarep.2016.05.009. Epub 2016 May 16. DNA Repair (Amst). 2016. PMID: 27233112 Review.

8

The DNA secondary structures at telomeres and genome instability.

Tan J, Lan L. Tan J, et al. Cell Biosci. 2020 Mar 26;10:47. doi: 10.1186/s13578-020-00409-z. eCollection 2020. Cell Biosci. 2020. PMID: 32257105 Free PMC article. Review.

9

Regulation of DNA break repair by transcription and RNA.

Ouyang J, Lan L, Zou L. Ouyang J, et al. Sci China Life Sci. 2017 Oct;60(10):1081-1086. doi: 10.1007/s11427-017-9164-1. Epub 2017 Oct 24. Sci China Life Sci. 2017. PMID: 29075944 Free PMC article. Review.

10

Guarding chromosomes from oxidative DNA damage to the very end.

Tan R, Lan L. Tan R, et al. Acta Biochim Biophys Sin (Shanghai). 2016 Jul;48(7):617-22. doi: 10.1093/abbs/gmw040. Epub 2016 May 12. Acta Biochim Biophys Sin (Shanghai). 2016. PMID: 27174872 Free PMC article. Review.

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