R01 GM120594/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	2
2018	2
2019	2
2020	1
2021	1
2022	2
2024	0

1

Structure and Mechanism of the Lipid Flippase MurJ.

Kuk ACY, Hao A, Lee SY. Kuk ACY, et al. Annu Rev Biochem. 2022 Jun 21;91:705-729. doi: 10.1146/annurev-biochem-040320-105145. Epub 2022 Mar 23. Annu Rev Biochem. 2022. PMID: 35320686 Free PMC article. Review.

2

Structures of Bacterial MraY and Human GPT Provide Insights into Rational Antibiotic Design.

Mashalidis EH, Lee SY. Mashalidis EH, et al. J Mol Biol. 2020 Aug 21;432(18):4946-4963. doi: 10.1016/j.jmb.2020.03.017. Epub 2020 Mar 19. J Mol Biol. 2020. PMID: 32199982 Free PMC article. Review.

3

Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY.

Nakaya T, Yabe M, Mashalidis EH, Sato T, Yamamoto K, Hikiji Y, Katsuyama A, Shinohara M, Minato Y, Takahashi S, Horiuchi M, Yokota SI, Lee SY, Ichikawa S. Nakaya T, et al. Nat Commun. 2022 Dec 20;13(1):7575. doi: 10.1038/s41467-022-35227-z. Nat Commun. 2022. PMID: 36539416 Free PMC article.

4

Lipid sugar carriers at the extremes: The phosphodolichols Archaea use in N-glycosylation.

Eichler J, Guan Z. Eichler J, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Jun;1862(6):589-599. doi: 10.1016/j.bbalip.2017.03.005. Epub 2017 Mar 19. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28330764 Free PMC article. Review.

5

GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.

Yoo J, Mashalidis EH, Kuk ACY, Yamamoto K, Kaeser B, Ichikawa S, Lee SY. Yoo J, et al. Nat Struct Mol Biol. 2018 Mar;25(3):217-224. doi: 10.1038/s41594-018-0031-y. Epub 2018 Feb 19. Nat Struct Mol Biol. 2018. PMID: 29459785 Free PMC article.

6

Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY.

Kwak SH, Lim WY, Hao A, Mashalidis EH, Kwon DY, Jeong P, Kim MJ, Lee SY, Hong J. Kwak SH, et al. Eur J Med Chem. 2021 Apr 5;215:113272. doi: 10.1016/j.ejmech.2021.113272. Epub 2021 Feb 6. Eur J Med Chem. 2021. PMID: 33607457 Free PMC article.

7

Visualizing conformation transitions of the Lipid II flippase MurJ.

Kuk ACY, Hao A, Guan Z, Lee SY. Kuk ACY, et al. Nat Commun. 2019 Apr 15;10(1):1736. doi: 10.1038/s41467-019-09658-0. Nat Commun. 2019. PMID: 30988294 Free PMC article.

8

Conformational plasticity in the selectivity filter of the TRPV2 ion channel.

Zubcevic L, Le S, Yang H, Lee SY. Zubcevic L, et al. Nat Struct Mol Biol. 2018 May;25(5):405-415. doi: 10.1038/s41594-018-0059-z. Epub 2018 Apr 30. Nat Struct Mol Biol. 2018. PMID: 29728656 Free PMC article.

9

Chemical logic of MraY inhibition by antibacterial nucleoside natural products.

Mashalidis EH, Kaeser B, Terasawa Y, Katsuyama A, Kwon DY, Lee K, Hong J, Ichikawa S, Lee SY. Mashalidis EH, et al. Nat Commun. 2019 Jul 2;10(1):2917. doi: 10.1038/s41467-019-10957-9. Nat Commun. 2019. PMID: 31266949 Free PMC article.

10

Crystal structure of the MOP flippase MurJ in an inward-facing conformation.

Kuk AC, Mashalidis EH, Lee SY. Kuk AC, et al. Nat Struct Mol Biol. 2017 Feb;24(2):171-176. doi: 10.1038/nsmb.3346. Epub 2016 Dec 26. Nat Struct Mol Biol. 2017. PMID: 28024149 Free PMC article.

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