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A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS.
Ocón B, Xiang M, Bi Y, Tan S, Brulois K, Ayesha A, Kunte M, Zhou C, LaJevic M, Lazarus N, Mengoni F, Sharma T, Montgomery S, Hooper JE, Huang M, Handel T, Dawson JRD, Kufareva I, Zabel BA, Pan J, Butcher EC. Ocón B, et al. Nature. 2024 Nov;635(8039):736-745. doi: 10.1038/s41586-024-08043-2. Epub 2024 Sep 18. Nature. 2024. PMID: 39293486
Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2.
Ortiz Zacarías NV, Chahal KK, Šimková T, van der Horst C, Zheng Y, Inoue A, Theunissen E, Mallee L, van der Es D, Louvel J, IJzerman AP, Handel TM, Kufareva I, Heitman LH. Ortiz Zacarías NV, et al. J Med Chem. 2021 Mar 11;64(5):2608-2621. doi: 10.1021/acs.jmedchem.0c01137. Epub 2021 Feb 18. J Med Chem. 2021. PMID: 33600174 Free PMC article.
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors.
Gray AL, Karlsson R, Roberts ARE, Ridley AJL, Pun N, Khan B, Lawless C, Luís R, Szpakowska M, Chevigné A, Hughes CE, Medina-Ruiz L, Birchenough HL, Mulholland IZ, Salanga CL, Yates EA, Turnbull JE, Handel TM, Graham GJ, Jowitt TA, Schiessl I, Richter RP, Miller RL, Dyer DP. Gray AL, et al. Cell Rep. 2023 Jan 31;42(1):111930. doi: 10.1016/j.celrep.2022.111930. Epub 2023 Jan 5. Cell Rep. 2023. PMID: 36640356 Free PMC article.
11 results