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Year Number of Results
2001 1
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2003 1
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2005 5
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2009 3
2010 1
2012 1
2024 0

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15 results

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Page 1
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.
Luthi-Carter R, Taylor DM, Pallos J, Lambert E, Amore A, Parker A, Moffitt H, Smith DL, Runne H, Gokce O, Kuhn A, Xiang Z, Maxwell MM, Reeves SA, Bates GP, Neri C, Thompson LM, Marsh JL, Kazantsev AG. Luthi-Carter R, et al. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7927-32. doi: 10.1073/pnas.1002924107. Epub 2010 Apr 8. Proc Natl Acad Sci U S A. 2010. PMID: 20378838 Free PMC article.
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS. Thompson LM, et al. J Cell Biol. 2009 Dec 28;187(7):1083-99. doi: 10.1083/jcb.200909067. Epub 2009 Dec 21. J Cell Biol. 2009. PMID: 20026656 Free PMC article.
A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo.
Zhang X, Smith DL, Meriin AB, Engemann S, Russel DE, Roark M, Washington SL, Maxwell MM, Marsh JL, Thompson LM, Wanker EE, Young AB, Housman DE, Bates GP, Sherman MY, Kazantsev AG. Zhang X, et al. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):892-7. doi: 10.1073/pnas.0408936102. Epub 2005 Jan 10. Proc Natl Acad Sci U S A. 2005. PMID: 15642944 Free PMC article.
A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer.
Najdi R, Syed A, Arce L, Theisen H, Ting JH, Atcha F, Nguyen AV, Martinez M, Holcombe RF, Edwards RA, Marsh JL, Waterman ML. Najdi R, et al. Oncogene. 2009 Nov 26;28(47):4133-46. doi: 10.1038/onc.2009.271. Epub 2009 Sep 14. Oncogene. 2009. PMID: 19749792 Free PMC article.
15 results