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The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway.
Mol Cancer Ther. 2011 Jun;10(6):949-59. doi: 10.1158/1535-7163.MCT-10-0904. Epub 2011 Apr 6.
Mol Cancer Ther. 2011.
PMID: 21471285
Free PMC article.
CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy.
Sakamoto KM, Frank DA.
Sakamoto KM, et al.
Clin Cancer Res. 2009 Apr 15;15(8):2583-7. doi: 10.1158/1078-0432.CCR-08-1137. Epub 2009 Apr 7.
Clin Cancer Res. 2009.
PMID: 19351775
Free PMC article.
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