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Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice.
Gil CH, Chakraborty D, Vieira CP, Prasain N, Li Calzi S, Fortmann SD, Hu P, Banno K, Jamal M, Huang C, Sielski MS, Lin Y, Huang X, Dupont MD, Floyd JL, Prasad R, Longhini ALF, McGill TJ, Chung HM, Murphy MP, Kotton DN, Boulton ME, Yoder MC, Grant MB. Gil CH, et al. Sci Adv. 2022 Mar 4;8(9):eabm5559. doi: 10.1126/sciadv.abm5559. Epub 2022 Mar 4. Sci Adv. 2022. PMID: 35245116 Free PMC article.
Osteopontin may be a driver of abdominal aortic aneurysm formation.
Wang SK, Green LA, Gutwein AR, Gupta AK, Babbey CM, Motaganahalli RL, Fajardo A, Murphy MP. Wang SK, et al. J Vasc Surg. 2018 Dec;68(6S):22S-29S. doi: 10.1016/j.jvs.2017.10.068. Epub 2018 Feb 3. J Vasc Surg. 2018. PMID: 29402664 Free article.
TSG-6 is highly expressed in human abdominal aortic aneurysms.
Wang SK, Xie J, Green LA, McCready RA, Motaganahalli RL, Fajardo A, Babbey CC, Murphy MP. Wang SK, et al. J Surg Res. 2017 Dec;220:311-319. doi: 10.1016/j.jss.2017.06.078. Epub 2017 Aug 12. J Surg Res. 2017. PMID: 29180197 Free PMC article.
Rationale and design of the Clinical and Histologic Analysis of Mesenchymal Stromal Cells in AmPutations (CHAMP) trial investigating the therapeutic mechanism of mesenchymal stromal cells in the treatment of critical limb ischemia.
Wang SK, Green LA, Drucker NA, Motaganahalli RL, Fajardo A, Murphy MP. Wang SK, et al. J Vasc Surg. 2018 Jul;68(1):176-181.e1. doi: 10.1016/j.jvs.2017.09.057. Epub 2018 Feb 1. J Vasc Surg. 2018. PMID: 29395424 Free PMC article. Clinical Trial.