Abnormal serum lipid profile in Brazilian police officers with post-traumatic stress disorder

J Affect Disord. 2008 Apr;107(1-3):259-63. doi: 10.1016/j.jad.2007.08.013. Epub 2007 Sep 20.

Abstract

Background: To measure the serum lipid composition of a sample of Brazilian police officers with and without PTSD regularly exposed to potentially traumatic situations.

Methods: A cross-sectional survey was conducted with 118 active duty male police officers. Serum concentrations for total cholesterol, LDL-C, HDL-C, and triglycerides were enzymatically determined. Body mass index (BMI) was obtained for each participant.

Results: Officers with PTSD exhibited significantly higher serum total cholesterol, LDL-C and triglycerides levels than those without PTSD. Total cholesterol and triglycerides, but not LDL-C, remained associated with PTSD diagnosis after controlling for confounding influences (i.e. socio-demographics, BMI, and tobacco, alcohol and medication use).

Limitations: The sample size was small. A nutritional interview was employed instead of established scales to assess alimentary habits, tobacco or alcohol consumption. A self-report screening tool was used to assess the prevalence of PTSD.

Conclusions: The association between PTSD and abnormal serum lipid profile and a tendency to exhibit higher BMI suggests that individuals with PTSD may be at increased risk for developing metabolic syndrome, a condition that by itself could account for many of the most serious PTSD-related physical health problems.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Adult
  • Alcohol Drinking / epidemiology
  • Alcohol Drinking / psychology
  • Body Mass Index
  • Brazil / epidemiology
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Comorbidity
  • Cross-Sectional Studies
  • Humans
  • Hyperlipidemias / blood
  • Hyperlipidemias / diagnosis
  • Hyperlipidemias / epidemiology
  • Life Change Events
  • Lipids / blood*
  • Male
  • Police / statistics & numerical data*
  • Smoking / epidemiology
  • Smoking / psychology
  • Stress Disorders, Post-Traumatic / blood*
  • Stress Disorders, Post-Traumatic / psychology
  • Triglycerides / blood

Substances

  • Adrenergic beta-Antagonists
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Lipids
  • Triglycerides