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Year Number of Results
2012 1
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2015 10
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28 results

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Page 1
Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma.
Grommes C, Pastore A, Palaskas N, Tang SS, Campos C, Schartz D, Codega P, Nichol D, Clark O, Hsieh WY, Rohle D, Rosenblum M, Viale A, Tabar VS, Brennan CW, Gavrilovic IT, Kaley TJ, Nolan CP, Omuro A, Pentsova E, Thomas AA, Tsyvkin E, Noy A, Palomba ML, Hamlin P, Sauter CS, Moskowitz CH, Wolfe J, Dogan A, Won M, Glass J, Peak S, Lallana EC, Hatzoglou V, Reiner AS, Gutin PH, Huse JT, Panageas KS, Graeber TG, Schultz N, DeAngelis LM, Mellinghoff IK. Grommes C, et al. Cancer Discov. 2017 Sep;7(9):1018-1029. doi: 10.1158/2159-8290.CD-17-0613. Epub 2017 Jun 15. Cancer Discov. 2017. PMID: 28619981 Free PMC article. Clinical Trial.
Toward precision medicine in glioblastoma: the promise and the challenges.
Prados MD, Byron SA, Tran NL, Phillips JJ, Molinaro AM, Ligon KL, Wen PY, Kuhn JG, Mellinghoff IK, de Groot JF, Colman H, Cloughesy TF, Chang SM, Ryken TC, Tembe WD, Kiefer JA, Berens ME, Craig DW, Carpten JD, Trent JM. Prados MD, et al. Neuro Oncol. 2015 Aug;17(8):1051-63. doi: 10.1093/neuonc/nov031. Epub 2015 May 1. Neuro Oncol. 2015. PMID: 25934816 Free PMC article. Review.
PI3K pathway inhibition in GBM—is there a signal?
Nichol D, Mellinghoff IK. Nichol D, et al. Neuro Oncol. 2015 Sep;17(9):1183-4. doi: 10.1093/neuonc/nov124. Epub 2015 Jul 12. Neuro Oncol. 2015. PMID: 26170259 Free PMC article. No abstract available.
Brain Malignancy Steering Committee clinical trials planning workshop: report from the Targeted Therapies Working Group.
Alexander BM, Galanis E, Yung WK, Ballman KV, Boyett JM, Cloughesy TF, Degroot JF, Huse JT, Mann B, Mason W, Mellinghoff IK, Mikkelsen T, Mischel PS, O'Neill BP, Prados MD, Sarkaria JN, Tawab-Amiri A, Trippa L, Ye X, Ligon KL, Berry DA, Wen PY. Alexander BM, et al. Neuro Oncol. 2015 Feb;17(2):180-8. doi: 10.1093/neuonc/nou154. Epub 2014 Aug 26. Neuro Oncol. 2015. PMID: 25165194 Free PMC article. Review.
Will kinase inhibitors make it as glioblastoma drugs?
Mellinghoff IK, Schultz N, Mischel PS, Cloughesy TF. Mellinghoff IK, et al. Curr Top Microbiol Immunol. 2012;355:135-69. doi: 10.1007/82_2011_178. Curr Top Microbiol Immunol. 2012. PMID: 22015553 Free PMC article. Review.
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.
Oldrini B, Hsieh WY, Erdjument-Bromage H, Codega P, Carro MS, Curiel-García A, Campos C, Pourmaleki M, Grommes C, Vivanco I, Rohle D, Bielski CM, Taylor BS, Hollmann TJ, Rosenblum M, Tempst P, Blenis J, Squatrito M, Mellinghoff IK. Oldrini B, et al. Nat Commun. 2017 Dec 11;8(1):2035. doi: 10.1038/s41467-017-02185-w. Nat Commun. 2017. PMID: 29229958 Free PMC article.
28 results