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Mitochondrial calcium exchange in physiology and disease.
Garbincius JF, Elrod JW. Garbincius JF, et al. Physiol Rev. 2022 Apr 1;102(2):893-992. doi: 10.1152/physrev.00041.2020. Epub 2021 Oct 26. Physiol Rev. 2022. PMID: 34698550 Free PMC article. Review.
MICU1 and MICU2 control mitochondrial calcium signaling in the mammalian heart.
Hasan P, Berezhnaya E, Rodríguez-Prados M, Weaver D, Bekeova C, Cartes-Saavedra B, Birch E, Beyer AM, Santos JH, Seifert EL, Elrod JW, Hajnóczky G. Hasan P, et al. Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2402491121. doi: 10.1073/pnas.2402491121. Epub 2024 Aug 20. Proc Natl Acad Sci U S A. 2024. PMID: 39163336
Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF).
Gibb AA, LaPenna K, Gaspar RB, Latchman NR, Tan Y, Choya-Foces C, Doiron JE, Li Z, Xia H, Lazaropoulos MP, Conwell M, Sharp TE 3rd, Goodchild TT, Lefer DJ, Elrod JW. Gibb AA, et al. bioRxiv [Preprint]. 2024 Oct 25:2024.10.25.619450. doi: 10.1101/2024.10.25.619450. bioRxiv. 2024. PMID: 39484400 Free PMC article. Preprint.