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Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration.
SanGiovanni JP, Arking DE, Iyengar SK, Elashoff M, Clemons TE, Reed GF, Henning AK, Sivakumaran TA, Xu X, DeWan A, Agrón E, Rochtchina E, Sue CM, Wang JJ, Mitchell P, Hoh J, Francis PJ, Klein ML, Chew EY, Chakravarti A. SanGiovanni JP, et al. PLoS One. 2009;4(5):e5508. doi: 10.1371/journal.pone.0005508. Epub 2009 May 12. PLoS One. 2009. PMID: 19434233 Free PMC article.