Framing expectations in early HIV cure research

Karine Dubé; Gail E Henderson; David M Margolis

doi:10.1016/j.tim.2014.08.003

Framing expectations in early HIV cure research

Trends Microbiol. 2014 Oct;22(10):547-9. doi: 10.1016/j.tim.2014.08.003.

Authors

Karine Dubé¹, Gail E Henderson², David M Margolis³

Affiliations

¹ Collaboratory of AIDS Researchers for Eradication (CARE), Institute for Global Health and Infectious Diseases (IGHID), The University of North Carolina at Chapel Hill, 120 Mason Farm Road, 2060 Genetic Medicine Building CB 7042, Chapel Hill, NC 27599-7042, USA.
² Department of Social Medicine, School of Medicine, The University of North Carolina at Chapel Hill, 347A MacNider, Campus Box 7240, Chapel Hill, NC 27599-7240, USA.
³ Collaboratory of AIDS Researchers for Eradication (CARE), Institute for Global Health and Infectious Diseases (IGHID), The University of North Carolina at Chapel Hill, 120 Mason Farm Road, 2060 Genetic Medicine Building CB 7042, Chapel Hill, NC 27599-7042, USA. Electronic address: [email protected].

Abstract

Language used to describe clinical research represents a powerful opportunity to educate volunteers. In the case of HIV cure research there is an emerging need to manage expectations by using the term 'experiment'. Cure experiments are proof-of-concept studies designed to evaluate novel paradigms to reduce persistent HIV-1 reservoirs, without any expectation of medical benefit.

Keywords: HIV cure research; expectations; experiments; trials.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Biomedical Research*
HIV Infections / therapy*
HIV Infections / virology
HIV-1 / physiology*
Humans

Abstract

Publication types

MeSH terms

Grants and funding