R01DK088133/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2011	2
2012	2
2013	4
2014	4
2015	4
2024	0

1

Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.

Gahete MD, Córdoba-Chacón J, Lin Q, Brüning JC, Kahn CR, Castaño JP, Christian H, Luque RM, Kineman RD. Gahete MD, et al. Endocrinology. 2013 Jul;154(7):2410-20. doi: 10.1210/en.2013-1261. Epub 2013 May 13. Endocrinology. 2013. PMID: 23671263 Free PMC article.

2

Elevated GH/IGF-I promotes mammary tumors in high-fat, but not low-fat, fed mice.

Gahete MD, Córdoba-Chacón J, Lantvit DD, Ortega-Salas R, Sanchez-Sanchez R, Pérez-Jiménez F, López-Miranda J, Swanson SM, Castaño JP, Luque RM, Kineman RD. Gahete MD, et al. Carcinogenesis. 2014 Nov;35(11):2467-73. doi: 10.1093/carcin/bgu161. Epub 2014 Aug 1. Carcinogenesis. 2014. PMID: 25085903 Free PMC article.

3

Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis).

Córdoba-Chacón J, Gahete MD, Castaño JP, Kineman RD, Luque RM. Córdoba-Chacón J, et al. Endocrinology. 2012 Jan;153(1):264-72. doi: 10.1210/en.2011-1677. Epub 2011 Nov 22. Endocrinology. 2012. PMID: 22109886 Free PMC article.

4

Truncated somatostatin receptor variant sst5TMD4 confers aggressive features (proliferation, invasion and reduced octreotide response) to somatotropinomas.

Luque RM, Ibáñez-Costa A, Neto LV, Taboada GF, Hormaechea-Agulla D, Kasuki L, Venegas-Moreno E, Moreno-Carazo A, Gálvez MÁ, Soto-Moreno A, Kineman RD, Culler MD, Gahete MD, Gadelha MR, Castaño JP. Luque RM, et al. Cancer Lett. 2015 Apr 10;359(2):299-306. doi: 10.1016/j.canlet.2015.01.037. Epub 2015 Jan 28. Cancer Lett. 2015. PMID: 25637790 Free PMC article.

5

Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice.

Cordoba-Chacon J, Majumdar N, List EO, Diaz-Ruiz A, Frank SJ, Manzano A, Bartrons R, Puchowicz M, Kopchick JJ, Kineman RD. Cordoba-Chacon J, et al. Diabetes. 2015 Sep;64(9):3093-103. doi: 10.2337/db15-0370. Epub 2015 May 26. Diabetes. 2015. PMID: 26015548 Free PMC article.

6

Islet insulin content and release are increased in male mice with elevated endogenous GH and IGF-I, without evidence of systemic insulin resistance or alterations in β-cell mass.

Cordoba-Chacon J, Majumdar N, Pokala NK, Gahete MD, Kineman RD. Cordoba-Chacon J, et al. Growth Horm IGF Res. 2015 Aug;25(4):189-95. doi: 10.1016/j.ghir.2015.04.002. Epub 2015 Apr 17. Growth Horm IGF Res. 2015. PMID: 25936582

7

Long- but not short-term adult-onset, isolated GH deficiency in male mice leads to deterioration of β-cell function, which cannot be accounted for by changes in β-cell mass.

Cordoba-Chacon J, Gahete MD, Pokala NK, Geldermann D, Alba M, Salvatori R, Luque RM, Kineman RD. Cordoba-Chacon J, et al. Endocrinology. 2014 Mar;155(3):726-35. doi: 10.1210/en.2013-1825. Epub 2013 Dec 16. Endocrinology. 2014. PMID: 24424062 Free PMC article.

8

Elevated GH/IGF-I, due to somatotrope-specific loss of both IGF-I and insulin receptors, alters glucose homeostasis and insulin sensitivity in a diet-dependent manner.

Gahete MD, Córdoba-Chacón J, Anadumaka CV, Lin Q, Brüning JC, Kahn CR, Luque RM, Kineman RD. Gahete MD, et al. Endocrinology. 2011 Dec;152(12):4825-37. doi: 10.1210/en.2011-1447. Epub 2011 Oct 11. Endocrinology. 2011. PMID: 21990313 Free PMC article.

9

Melatonin regulates somatotrope and lactotrope function through common and distinct signaling pathways in cultured primary pituitary cells from female primates.

Ibáñez-Costa A, Córdoba-Chacón J, Gahete MD, Kineman RD, Castaño JP, Luque RM. Ibáñez-Costa A, et al. Endocrinology. 2015 Mar;156(3):1100-10. doi: 10.1210/en.2014-1819. Epub 2014 Dec 29. Endocrinology. 2015. PMID: 25545385 Free PMC article.

10

The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice.

Gahete MD, Córdoba-Chacón J, Luque RM, Kineman RD. Gahete MD, et al. Endocrinology. 2013 Jan;154(1):263-9. doi: 10.1210/en.2012-1849. Epub 2012 Nov 13. Endocrinology. 2013. PMID: 23150490 Free PMC article.

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