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Obesity during childhood and adolescence increases susceptibility to multiple sclerosis after accounting for established genetic and environmental risk factors.
Gianfrancesco MA, Acuna B, Shen L, Briggs FB, Quach H, Bellesis KH, Bernstein A, Hedstrom AK, Kockum I, Alfredsson L, Olsson T, Schaefer C, Barcellos LF. Gianfrancesco MA, et al. Obes Res Clin Pract. 2014 Sep-Oct;8(5):e435-47. doi: 10.1016/j.orcp.2014.01.002. Epub 2014 Mar 6. Obes Res Clin Pract. 2014. PMID: 25263833 Free PMC article.
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects.
Patsopoulos NA, Barcellos LF, Hintzen RQ, Schaefer C, van Duijn CM, Noble JA, Raj T; IMSGC; ANZgene; Gourraud PA, Stranger BE, Oksenberg J, Olsson T, Taylor BV, Sawcer S, Hafler DA, Carrington M, De Jager PL, de Bakker PI. Patsopoulos NA, et al. PLoS Genet. 2013 Nov;9(11):e1003926. doi: 10.1371/journal.pgen.1003926. Epub 2013 Nov 21. PLoS Genet. 2013. PMID: 24278027 Free PMC article.
Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis.
Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Viña M, Ramsay PP, Khan O, Royal W 3rd, Hauser SL, Barcellos LF, Oksenberg JR. Caillier SJ, et al. J Immunol. 2008 Oct 15;181(8):5473-80. doi: 10.4049/jimmunol.181.8.5473. J Immunol. 2008. PMID: 18832704 Free PMC article.