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CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells.
Kluesner MG, Lahr WS, Lonetree CL, Smeester BA, Qiu X, Slipek NJ, Claudio Vázquez PN, Pitzen SP, Pomeroy EJ, Vignes MJ, Lee SC, Bingea SP, Andrew AA, Webber BR, Moriarity BS. Kluesner MG, et al. Nat Commun. 2021 Apr 23;12(1):2437. doi: 10.1038/s41467-021-22009-2. Nat Commun. 2021. PMID: 33893286 Free PMC article.