R21 CA159179/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2013	2
2014	4
2015	1
2016	2
2017	1
2019	1
2020	2
2021	1
2024	0

1

Phosphorylation-mediated regulation of GEFs for RhoA.

Patel M, Karginov AV. Patel M, et al. Cell Adh Migr. 2014;8(1):11-8. doi: 10.4161/cam.28058. Epub 2013 Jan 1. Cell Adh Migr. 2014. PMID: 24589508 Free PMC article. Review.

2

Optogenetics: The Art of Illuminating Complex Signaling Pathways.

Shaaya M, Fauser J, Karginov AV. Shaaya M, et al. Physiology (Bethesda). 2021 Jan 1;36(1):52-60. doi: 10.1152/physiol.00022.2020. Physiology (Bethesda). 2021. PMID: 33325819 Free PMC article. Review.

3

Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity.

Shaaya M, Fauser J, Zhurikhina A, Conage-Pough JE, Huyot V, Brennan M, Flower CT, Matsche J, Khan S, Natarajan V, Rehman J, Kota P, White FM, Tsygankov D, Karginov AV. Shaaya M, et al. Elife. 2020 Sep 23;9:e60647. doi: 10.7554/eLife.60647. Elife. 2020. PMID: 32965214 Free PMC article.

4

Dissecting Kinase Effector Signaling Using the RapRTAP Methodology.

Ray AM, Klomp JE, Collins KB, Karginov AV. Ray AM, et al. Methods Mol Biol. 2017;1636:21-33. doi: 10.1007/978-1-4939-7154-1_2. Methods Mol Biol. 2017. PMID: 28730470

5

Dissecting motility signaling through activation of specific Src-effector complexes.

Karginov AV, Tsygankov D, Berginski M, Chu PH, Trudeau ED, Yi JJ, Gomez S, Elston TC, Hahn KM. Karginov AV, et al. Nat Chem Biol. 2014 Apr;10(4):286-90. doi: 10.1038/nchembio.1477. Epub 2014 Mar 9. Nat Chem Biol. 2014. PMID: 24609359 Free PMC article.

6

Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis.

Collins KB, Kang H, Matsche J, Klomp JE, Rehman J, Malik AB, Karginov AV. Collins KB, et al. J Cell Biol. 2020 Feb 3;219(2):e201903023. doi: 10.1083/jcb.201903023. J Cell Biol. 2020. PMID: 31865373 Free PMC article.

7

Optochemical activation of kinase function in live cells.

Karginov AV, Hahn KM, Deiters A. Karginov AV, et al. Methods Mol Biol. 2014;1148:31-43. doi: 10.1007/978-1-4939-0470-9_3. Methods Mol Biol. 2014. PMID: 24718793 Free PMC article.

8

Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response.

Klomp JE, Shaaya M, Matsche J, Rebiai R, Aaron JS, Collins KB, Huyot V, Gonzalez AM, Muller WA, Chew TL, Malik AB, Karginov AV. Klomp JE, et al. Cell Chem Biol. 2019 Aug 15;26(8):1081-1094.e6. doi: 10.1016/j.chembiol.2019.04.007. Epub 2019 May 23. Cell Chem Biol. 2019. PMID: 31130521 Free PMC article.

9

Rational design of a ligand-controlled protein conformational switch.

Dagliyan O, Shirvanyants D, Karginov AV, Ding F, Fee L, Chandrasekaran SN, Freisinger CM, Smolen GA, Huttenlocher A, Hahn KM, Dokholyan NV. Dagliyan O, et al. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6800-4. doi: 10.1073/pnas.1218319110. Epub 2013 Apr 8. Proc Natl Acad Sci U S A. 2013. PMID: 23569285 Free PMC article.

10

Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae.

Zimnicka AM, Husain YS, Shajahan AN, Sverdlov M, Chaga O, Chen Z, Toth PT, Klomp J, Karginov AV, Tiruppathi C, Malik AB, Minshall RD. Zimnicka AM, et al. Mol Biol Cell. 2016 Jul 1;27(13):2090-106. doi: 10.1091/mbc.E15-11-0756. Epub 2016 May 11. Mol Biol Cell. 2016. PMID: 27170175 Free PMC article.

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