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Discovery and Optimization of Triazine Nitrile Inhibitors of Toxoplasma gondii Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS.
Zwicker JD, Smith D, Guerra AJ, Hitchens JR, Haug N, Vander Roest S, Lee P, Wen B, Sun D, Wang L, Keep RF, Xiang J, Carruthers VB, Larsen SD. Zwicker JD, et al. ACS Chem Neurosci. 2020 Aug 19;11(16):2450-2463. doi: 10.1021/acschemneuro.9b00674. Epub 2020 Feb 18. ACS Chem Neurosci. 2020. PMID: 32027110 Free PMC article.