R35 GM119561/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	1
2017	2
2018	5
2019	5
2020	3
2021	2
2022	1
2024	2
2025	0

1

Expanding the flexibility of base editing for high-throughput genetic screens in bacteria.

Gawlitt S, Collins SP, Yu Y, Blackman SA, Barquist L, Beisel CL. Gawlitt S, et al. Nucleic Acids Res. 2024 Apr 24;52(7):4079-4097. doi: 10.1093/nar/gkae174. Nucleic Acids Res. 2024. PMID: 38499498 Free PMC article.

2

CRISPR technologies and the search for the PAM-free nuclease.

Collias D, Beisel CL. Collias D, et al. Nat Commun. 2021 Jan 22;12(1):555. doi: 10.1038/s41467-020-20633-y. Nat Commun. 2021. PMID: 33483498 Free PMC article. Review.

3

A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13.

Vialetto E, Yu Y, Collins SP, Wandera KG, Barquist L, Beisel CL. Vialetto E, et al. Cell Host Microbe. 2022 Aug 10;30(8):1151-1162.e6. doi: 10.1016/j.chom.2022.05.013. Epub 2022 Jun 10. Cell Host Microbe. 2022. PMID: 35690065 Free PMC article.

4

Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs.

Jacobsen T, Ttofali F, Liao C, Manchalu S, Gray BN, Beisel CL. Jacobsen T, et al. Nucleic Acids Res. 2020 Jun 4;48(10):5624-5638. doi: 10.1093/nar/gkaa272. Nucleic Acids Res. 2020. PMID: 32329776 Free PMC article.

5

The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs.

Jacobsen T, Liao C, Beisel CL. Jacobsen T, et al. FEMS Microbiol Lett. 2019 Apr 1;366(8):fnz085. doi: 10.1093/femsle/fnz085. FEMS Microbiol Lett. 2019. PMID: 31004485 Free PMC article.

6

A detailed cell-free transcription-translation-based assay to decipher CRISPR protospacer-adjacent motifs.

Maxwell CS, Jacobsen T, Marshall R, Noireaux V, Beisel CL. Maxwell CS, et al. Methods. 2018 Jul 1;143:48-57. doi: 10.1016/j.ymeth.2018.02.016. Epub 2018 Feb 24. Methods. 2018. PMID: 29486239 Free PMC article.

7

Deciphering, Communicating, and Engineering the CRISPR PAM.

Leenay RT, Beisel CL. Leenay RT, et al. J Mol Biol. 2017 Jan 20;429(2):177-191. doi: 10.1016/j.jmb.2016.11.024. Epub 2016 Dec 1. J Mol Biol. 2017. PMID: 27916599 Free PMC article. Review.

8

CRATES: A one-step assembly method for Class 2 CRISPR arrays.

Liao C, Slotkowski RA, Beisel CL. Liao C, et al. Methods Enzymol. 2019;629:493-511. doi: 10.1016/bs.mie.2019.04.011. Epub 2019 Aug 5. Methods Enzymol. 2019. PMID: 31727255

9

CRISPR tool puts RNA on the record.

Beisel CL. Beisel CL. Nature. 2018 Oct;562(7727):347-349. doi: 10.1038/d41586-018-06869-1. Nature. 2018. PMID: 30323226 No abstract available.

10

Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes.

Patinios C, Gupta D, Bassett HV, Collins SP, Kamm C, Kibe A, Wang Y, Zhao C, Vollen K, Toussaint C, Polkoff KM, Nguyen T, Calvin I, Migur A, Al'Abri IS, Achmedov T, Del Re A, Saliba AE, Crook N, Stepanova AN, Alonso JM, Beisel CL. Patinios C, et al. bioRxiv [Preprint]. 2024 Nov 17:2024.11.17.623984. doi: 10.1101/2024.11.17.623984. bioRxiv. 2024. PMID: 39605674 Free PMC article. Preprint.

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