R35 GM141461/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2021	2
2022	2
2023	6
2024	3
2025	1

1

Karyopherin-mediated nucleocytoplasmic transport.

Wing CE, Fung HYJ, Chook YM. Wing CE, et al. Nat Rev Mol Cell Biol. 2022 May;23(5):307-328. doi: 10.1038/s41580-021-00446-7. Epub 2022 Jan 20. Nat Rev Mol Cell Biol. 2022. PMID: 35058649 Free PMC article. Review.

2

A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1.

Korff A, Yang X, O'Donovan K, Gonzalez A, Teubner BJ, Nakamura H, Messing J, Yang F, Carisey AF, Wang YD, Patni T, Sheppard H, Zakharenko SS, Chook YM, Taylor JP, Kim HJ. Korff A, et al. J Clin Invest. 2023 Jul 17;133(14):e160309. doi: 10.1172/JCI160309. J Clin Invest. 2023. PMID: 37463454 Free PMC article.

3

A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.

Gonzalez A, Kim HJ, Freibaum BD, Fung HYJ, Brautigam CA, Taylor JP, Chook YM. Gonzalez A, et al. Structure. 2023 Aug 3;31(8):924-934.e4. doi: 10.1016/j.str.2023.05.010. Epub 2023 Jun 5. Structure. 2023. PMID: 37279758 Free PMC article.

4

An update to the CRM1 cargo/NES database NESdb.

Fung HYJ, Niesman A, Chook YM. Fung HYJ, et al. Mol Biol Cell. 2021 Mar 15;32(6):467-469. doi: 10.1091/mbc.E20-11-0694. Mol Biol Cell. 2021. PMID: 33720780 Free PMC article. No abstract available.

5

Molecular basis of RanGTP-activated release of Histones H2A-H2B from Importin-9.

Shaffer JM, Jiou J, Tripathi K, Olaluwoye OS, Fung HYJ, Chook YM, D'Arcy S. Shaffer JM, et al. Structure. 2023 Aug 3;31(8):903-911.e3. doi: 10.1016/j.str.2023.06.001. Epub 2023 Jun 27. Structure. 2023. PMID: 37379840 Free PMC article.

6

WW domains: A globular NLS recognized by importin-α.

Bernardes NE, Chook YM. Bernardes NE, et al. J Cell Biol. 2024 Jun 3;223(6):e202405003. doi: 10.1083/jcb.202405003. Epub 2024 May 20. J Cell Biol. 2024. PMID: 38767621 Free PMC article.

7

Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).

Gonzalez A, Mannen T, Çağatay T, Fujiwara A, Matsumura H, Niesman AB, Brautigam CA, Chook YM, Yoshizawa T. Gonzalez A, et al. Sci Rep. 2021 Feb 12;11(1):3754. doi: 10.1038/s41598-021-83196-y. Sci Rep. 2021. PMID: 33580145 Free PMC article.

8

A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 is linked to neurodevelopmental disorders.

Gonzalez A, Kim HJ, Freibaum BD, Joyce Fung HY, Brautigam CA, Taylor JP, Chook YM. Gonzalez A, et al. bioRxiv [Preprint]. 2023 Jan 21:2023.01.20.524964. doi: 10.1101/2023.01.20.524964. bioRxiv. 2023. Update in: Structure. 2023 Aug 3;31(8):924-934.e4. doi: 10.1016/j.str.2023.05.010 PMID: 36711837 Free PMC article. Updated. Preprint.

9

Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.

Bernardes NE, Fung HYJ, Li Y, Chen Z, Chook YM. Bernardes NE, et al. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2207177119. doi: 10.1073/pnas.2207177119. Epub 2022 Sep 14. Proc Natl Acad Sci U S A. 2022. PMID: 36103578 Free PMC article.

10

Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.

Jiou J, Shaffer JM, Bernades NE, Fung HYJ, Kikumoto Dias J, D'Arcy S, Chook YM. Jiou J, et al. Proc Natl Acad Sci U S A. 2023 Jul 18;120(29):e2301199120. doi: 10.1073/pnas.2301199120. Epub 2023 Jul 14. Proc Natl Acad Sci U S A. 2023. PMID: 37450495 Free PMC article.

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