R35 NS111631/NS/NINDS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2019	6
2020	7
2021	10
2022	13
2023	10
2024	7

1

A Unified Model for the Function of YTHDF Proteins in Regulating m⁶A-Modified mRNA.

Zaccara S, Jaffrey SR. Zaccara S, et al. Cell. 2020 Jun 25;181(7):1582-1595.e18. doi: 10.1016/j.cell.2020.05.012. Epub 2020 Jun 2. Cell. 2020. PMID: 32492408 Free PMC article.

2

N⁶-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

Cheng Y, Xie W, Pickering BF, Chu KL, Savino AM, Yang X, Luo H, Nguyen DT, Mo S, Barin E, Velleca A, Rohwetter TM, Patel DJ, Jaffrey SR, Kharas MG. Cheng Y, et al. Cancer Cell. 2021 Jul 12;39(7):958-972.e8. doi: 10.1016/j.ccell.2021.04.017. Epub 2021 May 27. Cancer Cell. 2021. PMID: 34048709 Free PMC article.

3

m⁶A enhances the phase separation potential of mRNA.

Ries RJ, Zaccara S, Klein P, Olarerin-George A, Namkoong S, Pickering BF, Patil DP, Kwak H, Lee JH, Jaffrey SR. Ries RJ, et al. Nature. 2019 Jul;571(7765):424-428. doi: 10.1038/s41586-019-1374-1. Epub 2019 Jul 10. Nature. 2019. PMID: 31292544 Free PMC article.

4

Fluorogenic CRISPR for genomic DNA imaging.

Zhang Z, Rong X, Xie T, Li Z, Song H, Zhen S, Wang H, Wu J, Jaffrey SR, Li X. Zhang Z, et al. Nat Commun. 2024 Jan 31;15(1):934. doi: 10.1038/s41467-024-45163-9. Nat Commun. 2024. PMID: 38296979 Free PMC article.

5

Hidden codes in mRNA: Control of gene expression by m⁶A.

Murakami S, Jaffrey SR. Murakami S, et al. Mol Cell. 2022 Jun 16;82(12):2236-2251. doi: 10.1016/j.molcel.2022.05.029. Mol Cell. 2022. PMID: 35714585 Free PMC article. Review.

6

Highly efficient cellular expression of circular mRNA enables prolonged protein expression.

Unti MJ, Jaffrey SR. Unti MJ, et al. Cell Chem Biol. 2024 Jan 18;31(1):163-176.e5. doi: 10.1016/j.chembiol.2023.09.015. Epub 2023 Oct 25. Cell Chem Biol. 2024. PMID: 37883972

7

mTORC1 promotes cell growth via m⁶A-dependent mRNA degradation.

Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, Mathur L, Kim SS, Jung S, Tang HW, Monette S, Rabinowitz JD, Perrimon N, Jaffrey SR, Blenis J. Cho S, et al. Mol Cell. 2021 May 20;81(10):2064-2075.e8. doi: 10.1016/j.molcel.2021.03.010. Epub 2021 Mar 22. Mol Cell. 2021. PMID: 33756105 Free PMC article.

8

Live imaging of mRNA using RNA-stabilized fluorogenic proteins.

Wu J, Zaccara S, Khuperkar D, Kim H, Tanenbaum ME, Jaffrey SR. Wu J, et al. Nat Methods. 2019 Sep;16(9):862-865. doi: 10.1038/s41592-019-0531-7. Epub 2019 Aug 30. Nat Methods. 2019. PMID: 31471614 Free PMC article.

9

Caspase-11 interaction with NLRP3 potentiates the noncanonical activation of the NLRP3 inflammasome.

Moretti J, Jia B, Hutchins Z, Roy S, Yip H, Wu J, Shan M, Jaffrey SR, Coers J, Blander JM. Moretti J, et al. Nat Immunol. 2022 May;23(5):705-717. doi: 10.1038/s41590-022-01192-4. Epub 2022 Apr 29. Nat Immunol. 2022. PMID: 35487985 Free PMC article.

10

mRNA ageing shapes the Cap2 methylome in mammalian mRNA.

Despic V, Jaffrey SR. Despic V, et al. Nature. 2023 Feb;614(7947):358-366. doi: 10.1038/s41586-022-05668-z. Epub 2023 Feb 1. Nature. 2023. PMID: 36725932 Free PMC article.

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